ID   A0A2V3VXP7_9PROT        Unreviewed;       501 AA.
AC   A0A2V3VXP7;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Cobalt-zinc-cadmium efflux system membrane fusion protein {ECO:0000313|EMBL:PXW86793.1};
GN   ORFNames=C8R34_11366 {ECO:0000313|EMBL:PXW86793.1};
OS   Nitrosomonas sp. Nm84.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=200124 {ECO:0000313|EMBL:PXW86793.1, ECO:0000313|Proteomes:UP000248024};
RN   [1] {ECO:0000313|EMBL:PXW86793.1, ECO:0000313|Proteomes:UP000248024}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nm84 {ECO:0000313|EMBL:PXW86793.1,
RC   ECO:0000313|Proteomes:UP000248024};
RA   Wagner M.;
RT   "Active sludge and wastewater microbial communities from Klosterneuburg,
RT   Austria.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000256|ARBA:ARBA00009477}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PXW86793.1}.
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DR   EMBL; QJJP01000013; PXW86793.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2V3VXP7; -.
DR   Proteomes; UP000248024; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.420.20; -; 1.
DR   Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR   InterPro; IPR032317; HlyD_D23.
DR   InterPro; IPR006143; RND_pump_MFP.
DR   NCBIfam; TIGR01730; RND_mfp; 1.
DR   PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR   PANTHER; PTHR30097:SF4; SLR6042 PROTEIN; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
DR   SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248024};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          182..415
FT                   /note="RND efflux pump membrane fusion protein barrel-
FT                   sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF16576"
SQ   SEQUENCE   501 AA;  54645 MW;  C7F119B7256C4F30 CRC64;
     MNKARWMPIL VVIGIGIVLG GLILTLDKPT AVTADAASAN TNTNEKLAEN QTGTGPRGGK
     LFTDNDFSVE LTIFEKGVPP QFRVYLYEKG KLLPPAAATV AITLSRLGAS AQLFKLTPEA
     DYLLGDQVVE EPHSFDIAIA AERNGKLMRW SYSQVEGRVE IPDTMLKSMG IEVLTAGPAI
     IKPKLKLPGE VIFNEHNIVR VVPRAPGMVT AVYGHHGQQV KKGDVLAVVE SPMLADLRSQ
     YFVAKKRLTL AKTTYEREKQ LWEEKITAKQ EFLLAQELWN EAEIALELAS TKLRALGVQP
     ESSRLGADIV HYEIRSPISG IIIAKAIALG EALKEDREIY TVADVSTVWT AITVYPKDLN
     VIRVGQKVAV KATAFDVEGE GTVTYISTLI GGQTRTATAR VELDNTADRW RPGMFINAEL
     VAEEIAVPVA VSVAAIQTLR DWSVVFGRYD PYFEVRPLEL GRADGDMVEV LKGLTRGEQY
     AGGNSFALKA ELGKAGASHD H
//