ID A0A2V3WEN6_9BACI Unreviewed; 194 AA.
AC A0A2V3WEN6;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=AraC family transcriptional regulator of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase {ECO:0000313|EMBL:PXW90685.1};
GN ORFNames=DFR56_101599 {ECO:0000313|EMBL:PXW90685.1};
OS Pseudogracilibacillus auburnensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Pseudogracilibacillus.
OX NCBI_TaxID=1494959 {ECO:0000313|EMBL:PXW90685.1, ECO:0000313|Proteomes:UP000247978};
RN [1] {ECO:0000313|EMBL:PXW90685.1, ECO:0000313|Proteomes:UP000247978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 28556 {ECO:0000313|EMBL:PXW90685.1,
RC ECO:0000313|Proteomes:UP000247978};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PXW90685.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QJJQ01000001; PXW90685.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V3WEN6; -.
DR OrthoDB; 9802228at2; -.
DR Proteomes; UP000247978; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.10.10; DNA Methylphosphotriester Repair Domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR035451; Ada-like_dom_sf.
DR InterPro; IPR004026; Ada_DNA_repair_Zn-bd.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR016220; Me-P-triester_DNA_alkyl-Trfase.
DR PANTHER; PTHR43280; ARAC-FAMILY TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR43280:SF2; BIFUNCTIONAL TRANSCRIPTIONAL ACTIVATOR_DNA REPAIR ENZYME ADAA; 1.
DR Pfam; PF02805; Ada_Zn_binding; 1.
DR Pfam; PF12833; HTH_18; 1.
DR PIRSF; PIRSF000408; Alkyltransferas_AdaA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SUPFAM; SSF57884; Ada DNA repair protein, N-terminal domain (N-Ada 10); 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:PXW90685.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000247978};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:PXW90685.1}.
FT DOMAIN 89..187
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
SQ SEQUENCE 194 AA; 22670 MW; 621EDF22C1131DBA CRC64;
MKILNNMSKE IMWEAVVTCD PKYDGEFLYA IKTTGIFCRP SCRSKIPKYK NVSFYTNAEE
AQLAGYRPCK RCRPDLSLKN YDPLHSIIKD TKEIIENQYW KNIHLNDIAA KVGVSQFHLT
RTFKNRTGYT PRLYLEKIRI RKAQELLMTT TLSSTEIGFQ IGYQSMSSFY HAFKRHTGHS
PRQFQADIKN NLKP
//
