ID A0A2V3WGG3_9PROT Unreviewed; 388 AA.
AC A0A2V3WGG3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=C8R34_101247 {ECO:0000313|EMBL:PXW91335.1};
OS Nitrosomonas sp. Nm84.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosomonas.
OX NCBI_TaxID=200124 {ECO:0000313|EMBL:PXW91335.1, ECO:0000313|Proteomes:UP000248024};
RN [1] {ECO:0000313|EMBL:PXW91335.1, ECO:0000313|Proteomes:UP000248024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nm84 {ECO:0000313|EMBL:PXW91335.1,
RC ECO:0000313|Proteomes:UP000248024};
RA Wagner M.;
RT "Active sludge and wastewater microbial communities from Klosterneuburg,
RT Austria.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PXW91335.1}.
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DR EMBL; QJJP01000001; PXW91335.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V3WGG3; -.
DR Proteomes; UP000248024; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000248024}.
FT DOMAIN 42..377
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 388 AA; 43016 MW; 991BEEA373974736 CRC64;
MVTIKSAPNN KVRTILTLFG TRPEIIKLAP VIWAIERRKD VWRSVAVSSS QHTDLLRPFI
REFNISIDYD LAVMTPNQTP SSVLARIVEA MEQLLLAKRP NLVLVQGDTT TAIAGALAAF
YARIPVAHVE AGLRTDNRHS PFPEEMNRRL ITQLADLHFA ATSKNVDILL AEGVKKECVA
LTGNPVVDSL QHVLRRSTAS PKLSQLLDSI SSKHLIVLTT HRRENFGQVM SSHLKALRRF
VKRHRDVELV FPVHPNPSVR AAVDAEFSGA ERIHCIEPLE YTDFLHLLSR AWLVVSDSGG
VQEEVPSLGK PLLVLRDTTE RPEVLECGVG RLVGHSGERL EEMLETALVD QAWFDTVRTT
ENPFGKGDAG EQIASAIAQF FAADKGDT
//
