ID   A0A2V3WTG3_9BACI        Unreviewed;       435 AA.
AC   A0A2V3WTG3;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   24-JAN-2024, entry version 11.
DE   SubName: Full=GHKL domain-containing protein {ECO:0000313|EMBL:PXW92101.1};
GN   ORFNames=DES38_103116 {ECO:0000313|EMBL:PXW92101.1};
OS   Streptohalobacillus salinus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Streptohalobacillus.
OX   NCBI_TaxID=621096 {ECO:0000313|EMBL:PXW92101.1, ECO:0000313|Proteomes:UP000247922};
RN   [1] {ECO:0000313|EMBL:PXW92101.1, ECO:0000313|Proteomes:UP000247922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22440 {ECO:0000313|EMBL:PXW92101.1,
RC   ECO:0000313|Proteomes:UP000247922};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT   most valuable type-strain genomes for metagenomic binning, comparative
RT   biology and taxonomic classification.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PXW92101.1}.
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DR   EMBL; QJJR01000003; PXW92101.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2V3WTG3; -.
DR   OrthoDB; 9813149at2; -.
DR   Proteomes; UP000247922; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd16935; HATPase_AgrC-ComD-like; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR032834; NatK_C.
DR   PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   Pfam; PF14501; HATPase_c_5; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000247922};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        35..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        60..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        120..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        161..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          327..432
FT                   /note="Sensor histidine kinase NatK C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14501"
SQ   SEQUENCE   435 AA;  50299 MW;  0DC0D9486842EE67 CRC64;
     MSEFFPEIPR ILTALTEWMA CLVYVLILKK KIKGFRLPLF LVGALVIQAS FLMATGNLDI
     FFWVPSMIVA ILLMILLIHQ TTDVSLYEAG YFGIKAFVAA ELVASFHWQV HYYLIREDNV
     YSLAGMSLLI LVYGLSFFLI WFLEKRHMPE EGKLYIKARE FWSTATIGFA VFFISNLSFV
     SIRTPFSGQY AAEILNIRTL VDLGGFAILF AYHVQINELR VKHELEAMQN IFQNQYTQYQ
     QSKESIELIN YKYHDLKNQL IAIKAETDPE KREAYIDDMQ SGIKTFEAQH KTGNQVVDTM
     LTTKHMYCIK NNITLTSVAD GHLLDKMDVA DICTIFGNAL DNAIEYEMKV KDIEKRLIHL
     TLHEQNNFVL IQIENYYEGN LELADALPHT TKKDKQNHGY GLKSIRHTVQ KYDGIVKLNH
     KNHWFQLTVL IPKLK
//