ID A0A2V4B2X9_9PSEU Unreviewed; 768 AA.
AC A0A2V4B2X9;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Molybdopterin-dependent oxidoreductase alpha subunit {ECO:0008006|Google:ProtNLM};
GN ORFNames=BAY60_13870 {ECO:0000313|EMBL:PXY28387.1};
OS Prauserella muralis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Prauserella.
OX NCBI_TaxID=588067 {ECO:0000313|EMBL:PXY28387.1, ECO:0000313|Proteomes:UP000249915};
RN [1] {ECO:0000313|EMBL:PXY28387.1, ECO:0000313|Proteomes:UP000249915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45305 {ECO:0000313|EMBL:PXY28387.1,
RC ECO:0000313|Proteomes:UP000249915};
RA Ruckert C., Albersmeier A., Jiang C.-L., Jiang Y., Kalinowski J.,
RA Schneider O., Winkler A., Zotchev S.B.;
RT "Draft genome sequence of Prauserella muralis DSM 45305, isolated from a
RT mould-covered wall in an indoor environment.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PXY28387.1}.
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DR EMBL; MASW01000002; PXY28387.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V4B2X9; -.
DR OrthoDB; 5287431at2; -.
DR Proteomes; UP000249915; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR CDD; cd02787; MopB_CT_ydeP; 1.
DR CDD; cd02767; MopB_ydeP; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR037951; MopB_CT_YdeP.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR InterPro; IPR041953; YdeP_MopB.
DR NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR PIRSF; PIRSF000144; CbbBc; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000249915}.
FT DOMAIN 125..510
FT /note="Molybdopterin oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00384"
FT DOMAIN 654..759
FT /note="Molybdopterin dinucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF01568"
SQ SEQUENCE 768 AA; 83739 MW; 477AA4E0CE02B679 CRC64;
MARNAPHDDI DEGRLEVGKP KEWAAGLPGV AVSLRRSWEQ MGAGRTVRTL RLLNQRDGYD
CPGCAWPEPR EADGEHRKLA EFCENGAKAV AEEATTRRVG PEFFARHSVA ELAERSDYWL
GQQGRLTHPM VLREGATHYE PVSWDEALRL TADALRGLSD PNQAIFYTSG RTSNEAAFAY
QLLVRSFGTN NLPDCSNMCH ESSGAALTES TGIGKGTVSL ADVHHADLIV VIGQNPGTNH
PRMLSALERA KAGGARVVAV NPLPEAGLMR FKNPQNVRGV LGKGSPLADE FCQIRLGGDL
ALFQAIGHLL LTWDDAAPGT VLDHDFIGSS THDFADYAKQ LRELDWAEVE QATGVSREQI
ARIASMIASS ERTVYCWAMG LTQHRHAVPT IREVANVALL RGMIGKPGAG LCPVRGHSNV
QGDRTMGIWE KMPEEFLAAL EAEFGIDVPR EHGWDVVDSI RAMREGRGRV FFALGGNFAS
ATPDTAATER ALRSCELTVH VSTKLNRSHA VTGRTALILP TLGRTERDVQ ASGEQFVTVE
DSMSAVHASR GRIAPASEHL LSEVAILCRL ARELFGEAHP VPWREFEAGY DAIRDRIARV
VPGCEDYNAR VREPDGFVLP NPPRDAREFT GTLTGKAMFS VNDLEYPRVP EGRLLLQTLR
SHDQYNTTIY GLSDRYRGVE DGRRVVFVNP ADLAALGVAD GTLVDLVSEA DDGDRRAERF
RVVSYPTAPG CAAAYFPEAN ALVPLDAVAR TSNTPASKAI VVRLEPTA
//
