ID A0A2V4BJK4_9FLAO Unreviewed; 494 AA.
AC A0A2V4BJK4;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Alpha-L-fucosidase {ECO:0000313|EMBL:PXY39166.1};
GN ORFNames=DMB65_19045 {ECO:0000313|EMBL:PXY39166.1};
OS Flavobacterium cheongpyeongense.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=2212651 {ECO:0000313|EMBL:PXY39166.1, ECO:0000313|Proteomes:UP000247903};
RN [1] {ECO:0000313|EMBL:PXY39166.1, ECO:0000313|Proteomes:UP000247903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC34759 {ECO:0000313|EMBL:PXY39166.1,
RC ECO:0000313|Proteomes:UP000247903};
RA Joung Y., Cho J.;
RT "Flavobacterium sp. strain IMCC34759, incomplete genome.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PXY39166.1}.
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DR EMBL; QJHK01000023; PXY39166.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V4BJK4; -.
DR OrthoDB; 1095333at2; -.
DR Proteomes; UP000247903; Unassembled WGS sequence.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR031919; Fucosidase_C.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR Pfam; PF16757; Fucosidase_C; 1.
DR PIRSF; PIRSF001092; Alpha-L-fucosidase; 2.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000247903};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..494
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016130207"
FT DOMAIN 407..490
FT /note="Alpha-L-fucosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16757"
FT SITE 326
FT /note="May be important for catalysis"
FT /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ SEQUENCE 494 AA; 56959 MW; 1D86B993E83B622D CRC64;
MKKRIAIIAL LFSAQLFSQA IYEDERYVPE TDPAVLKNLE EWQGKKFGLL MHWGTYSQWG
IVESWSICPE DYGWCERKKG SNPANYNQYV SDYEGLKKTF NPVKFDPVKW AKAAKYAGMK
YMVFTTKHHD GFNMYDTKYS DYKVTDKECP FSTNEKADIL KEVFNAFRTE NISTGAYFSK
PDWHNENYWD PYFPPFDRNV NYDPALYPEK WQKYVDFTHN QILEILTNYG KVDILWLDGG
WVRKRDQQNI KENYDEKFAE NEAKNGFIKH RVVNQDPKMD ELVVKARQKQ PGLIVVDRAV
HGINQNYLTP ENRVPEKTLP YPWESCITSG GGWSYTPDAT YLTGRQGIHM LIDVVAKGGN
LLLNVAPSPE GEWQKGAYDL LQAYGDWMKV NSTAIYNTKP IEPFKEDNIC LTQNKAGNVF
AFYLAKEGED KIPAEVSVKS ISPKKGTKIT MLGSKTSLKW VKSDKGFTVT IPESLRNNLP
AKEAWTLKIE AINR
//
