ID A0A2V4BSX2_9FLAO Unreviewed; 1446 AA.
AC A0A2V4BSX2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DMB65_02680 {ECO:0000313|EMBL:PXY42158.1};
OS Flavobacterium cheongpyeongense.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=2212651 {ECO:0000313|EMBL:PXY42158.1, ECO:0000313|Proteomes:UP000247903};
RN [1] {ECO:0000313|EMBL:PXY42158.1, ECO:0000313|Proteomes:UP000247903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC34759 {ECO:0000313|EMBL:PXY42158.1,
RC ECO:0000313|Proteomes:UP000247903};
RA Joung Y., Cho J.;
RT "Flavobacterium sp. strain IMCC34759, incomplete genome.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PXY42158.1}.
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DR EMBL; QJHK01000002; PXY42158.1; -; Genomic_DNA.
DR OrthoDB; 1108380at2; -.
DR Proteomes; UP000247903; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF07494; Reg_prop; 2.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 2.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000247903};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1446
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015902528"
FT TRANSMEM 889..910
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 940..1153
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1195..1310
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1345..1444
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT MOD_RES 1243
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1446 AA; 165093 MW; D0F9425258509E62 CRC64;
MLKRNILVLF LYLVCTLCTS QPSGILTHFS NDLKLSQSRI LGIQQDEKGF IWLGTFNGLI
RYDGNTFQNF RVEKGASLDL MSNRVSKFKF DKKGRIWIQS EKNDIYYFDT HQLKFHYPIE
GKSVKSYNTA LKKFKIMPSG RVWLFTEDKN YLIAFQNNKQ IRKIIFDPAK HCGTIWDAFE
DALGTTWFLT DAGICRLNKS GTAPEYFFLN MSGHSGKSYS FNSFLETADD IWFGGDMGKF
TRYTKKSSTF FDFDLGIKED IALIKLVGNS KVLIITRGKE FYFYDIKAGK LNLYNSKTLP
GFPGEKVNYL GITHSRQFWF ETPNSGVFQF DLVTRKLKHM EVDFNGPPVV GAEQKSFLLT
SPDGTVWMQS HKGPFSYWDE KQNKLSSVIR CIKESKETIS DVMHTAMFDK LGNLWFCSFK
QGLDQITFNN RNFSTLNLHT SGDGKKQNVR SLMNDKNGNL WVASRSEKIA IFDSQKKKIG
LLGSDGILSN GSPGWGADIY SMMQDSNGRI WIGTRGNGLF CLTPGGQPFK YKVNHYKYDE
KDIYSINSDD IYKIFQASNG QIYVATWGGG INLVRQSNNG FRFINHKNEL KNYPIKNADK
VRSIVENKEH ELFFISSYKL FSFSAENKSP DKIQFKEFSQ VSGNDILDIL ITSDNRLALA
TNGKGLILGD LDQKGQLKVK SIWNKNVAFP IEGVVALQED KLGKIWLMSV NQIVRFDPKK
NSAETFPELK SIIGTEIFSE ATKCRLSNGE ILVGYSDGAL YFKPEAIKPF QFKPYLAISG
FSVNDKQLHE INPETPGNPD LLKKVMLEHN QNFFRVQISA LDYIKNENIV YRYKLEGVDK
QWNYLKGGQS INYTNLDRGK YTLIVSSTNG HNLWADNERR IKITIRPSIW GTNFAYFCYL
LLAIGLFLVV RRAIATILRL RNDVKLQKQM SELKLKFFTD ISHEIRTPLT MITAPLEIML
SDDDIKDSVK DQLRVIEKNS NKLLNLVNQI LDLRRIQDRK LVVSEIDLGE FAAKIGENFS
EMSIQRNIEL KINIGTSKPT IWADPDSLDK ILVNLLSNAF KYCHKGDTVQ VEVKESEKQV
VLKVSDNGPG ISPILQKRLF IRFSNYNENP YNPSTGIGLS IVKDLADKHG ATILVDSVPG
KGSSFQICFL KGYKHFTEDV DILFEEDEAD LVNDMKFENE PDLISFVEIE NEMPVGLIVE
DDPELRGFIV SVLEKEYTIY VAENGAEGNL KAAELSPDFI ISDIMMPHLD GIEMLKLIRN
NFATSHIPVI LLSAKTAIES KLEGMEYGAD DYITKPFNVS FLKARVKNVL EQRLRLQHLY
STGNMTEISE EEPLQISNKD HKFMFQVIKL VKENMSKSDF SVDELGRLMC MSRASFFNKL
KSITGVSPVV FIRDMRLNEA AELIKNEDLL IKEICFEVGF NDQKYFGKCF RAKFNCTPAE
YRRQFC
//
