ID A0A2V4MWJ4_9RHOB Unreviewed; 668 AA.
AC A0A2V4MWJ4;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Biotin carboxylase {ECO:0000313|EMBL:PYC46854.1};
GN ORFNames=DI396_12895 {ECO:0000313|EMBL:PYC46854.1};
OS Litorivita pollutaquae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Litorivita.
OX NCBI_TaxID=2200892 {ECO:0000313|EMBL:PYC46854.1, ECO:0000313|Proteomes:UP000248012};
RN [1] {ECO:0000313|EMBL:PYC46854.1, ECO:0000313|Proteomes:UP000248012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FSX-11 {ECO:0000313|EMBL:PYC46854.1,
RC ECO:0000313|Proteomes:UP000248012};
RA Hetharua B.H., Min D., Liao H., Tian Y.;
RT "Oceanovita maritima gen. nov., sp. nov., a marine bacterium in the family
RT Rhodobacteraceae isolated from surface seawater of Lundu port Xiamen,
RT China.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=biotin; Xref=ChEBI:CHEBI:57586;
CC Evidence={ECO:0000256|ARBA:ARBA00001953};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PYC46854.1}.
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DR EMBL; QFVT01000009; PYC46854.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V4MWJ4; -.
DR OrthoDB; 9763189at2; -.
DR Proteomes; UP000248012; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR005481; BC-like_N.
DR InterPro; IPR011764; Biotin_carboxylation_dom.
DR InterPro; IPR005482; Biotin_COase_C.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR011054; Rudment_hybrid_motif.
DR InterPro; IPR011053; Single_hybrid_motif.
DR PANTHER; PTHR18866; CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE; 1.
DR PANTHER; PTHR18866:SF33; METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF02785; Biotin_carb_C; 1.
DR Pfam; PF00289; Biotin_carb_N; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF02786; CPSase_L_D2; 1.
DR SMART; SM00878; Biotin_carb_C; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR SUPFAM; SSF51246; Rudiment single hybrid motif; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS50979; BC; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS00867; CPSASE_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Reference proteome {ECO:0000313|Proteomes:UP000248012}.
FT DOMAIN 2..444
FT /note="Biotin carboxylation"
FT /evidence="ECO:0000259|PROSITE:PS50979"
FT DOMAIN 121..317
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT DOMAIN 590..664
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
SQ SEQUENCE 668 AA; 71075 MW; 688C49B0B8F1EABB CRC64;
MKIKTLLIAN RGEIACRIAR TARASGITPV GVHSDADANA LHVREIGHSV CIGAGPASES
YLKIDAVIAA AKSVGADAIH PGYGFLAENS DFARAVEAAG MVFMGPTPDT LERFGDKASA
KEAAVAASVP VISGAEGARS DPQEIAEEVR AMGLPVLLKA VGGGGGRGQR LVTDETTLVE
DIEGALREAK STFGSEGLLL ERFLPEARHV EVQIAGDGKG HVVHLFERDC TLQRRHQKVI
EEAPAWGLPR TLLDKIAQDA VRLGETLDYR GLGTVEFLVA GEEYFFLEVN PRIQVEHPVT
EAITGLDLVA LHLRIAEGAG LGLVQDDLKI NGHAVEARLY AEDPAMQFAP STGTLTTLSL
PEGLRIDSGV EEGDAVTPFY DPMIAKLVVH AADRETALAR LATALDHVAV EGVQTNRAFL
TALARNPEFE QMQVHTRWID GRLDELTQAH TLSRPALWKA AAAILFVAAS RSDASTNPWT
NRDTFTGWRL GLGGDAMEAG QHVTLTDAAD TSEEFRVGPI KAVDTYTVMS ENGDALTLAM
REITPGRWRI SDGDDVFLID ARLHAGVIEM DTPEGRLVFR PAAPLDFAGG DAAGDRAVAS
PLTGMIVEIK VADGQDVTEG DVIAVMESMK LEISIRATAA GIASNISVSN GDMVDRGQVI
AEILPSEE
//
