ID A0A2V4N231_9ACTN Unreviewed; 556 AA.
AC A0A2V4N231;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Acyl-CoA dehydrogenase {ECO:0000313|EMBL:PYC78000.1};
GN ORFNames=C7C46_16795 {ECO:0000313|EMBL:PYC78000.1};
OS Streptomyces tateyamensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=565073 {ECO:0000313|EMBL:PYC78000.1, ECO:0000313|Proteomes:UP000248039};
RN [1] {ECO:0000313|EMBL:PYC78000.1, ECO:0000313|Proteomes:UP000248039}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 21389 {ECO:0000313|EMBL:PYC78000.1,
RC ECO:0000313|Proteomes:UP000248039};
RA Schwalen C.J., Hudson G.A., Mitchell D.A.;
RT "Bioinformatic expansion and discovery of thiopeptide antibiotics.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|RuleBase:RU362125};
CC -!- SIMILARITY: Belongs to the acyl-CoA dehydrogenase family.
CC {ECO:0000256|RuleBase:RU362125}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PYC78000.1}.
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DR EMBL; PYBW01000053; PYC78000.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V4N231; -.
DR OrthoDB; 3666321at2; -.
DR Proteomes; UP000248039; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.540.10; Acyl-CoA dehydrogenase/oxidase, N-terminal domain; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009075; AcylCo_DH/oxidase_C.
DR InterPro; IPR037069; AcylCoA_DH/ox_N_sf.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR PANTHER; PTHR43884; ACYL-COA DEHYDROGENASE; 1.
DR PANTHER; PTHR43884:SF12; COMPLEX I ASSEMBLY FACTOR ACAD9, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00441; Acyl-CoA_dh_1; 1.
DR Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU362125};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU362125};
KW Oxidoreductase {ECO:0000256|RuleBase:RU362125};
KW Reference proteome {ECO:0000313|Proteomes:UP000248039}.
FT DOMAIN 123..214
FT /note="Acyl-CoA oxidase/dehydrogenase middle"
FT /evidence="ECO:0000259|Pfam:PF02770"
FT DOMAIN 231..365
FT /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00441"
SQ SEQUENCE 556 AA; 58112 MW; 2637333FC6830F45 CRC64;
MIEALTAKAA ALELLLGDAG DPANPYGFAA AARRDEREEF PAEYAAVLRE AGFHLDYLPP
AWGGGFESFD RSLQLVRSAA RRDLNAMPAT MFSITAATCL RLHGSAAQQD RAAAVLRRGG
AVGFALSEAE HGSDLLANAV RLVADGAGYR LDGTKWMVGL GQRCEALYLV ARTGDRGPGA
FSALLLDTTG LDRGAPVRTS GMRGIDFAHL AFDQLPVSAA DLVGRQGEAL EVAVKAQQVV
RVMSTAGSLG VADTALRLTL DFAAERRLGR TALLDTPYQR RELALASAAL LAADAVALAA
ARGIHVVPEQ FSVWGCAAKH VVAEAVDDVL ARCAATLASR AVLRGEGPGG GLFQKLRRDA
ELVRVVDTSP LANLRSFAGQ LPSLAEPVGE RAAAATAFAL DAELPPYDPA RLDLTARGKE
LVTGGLAESA EAARAELAGA PAVVALVDQL LTALAGLPTT PTTGCAQLDL AERFAWLHAA
AACLRLWWAN RHLPLHGGKP GSPDWLGACL GYLLARADGA DPRRCADTAP AALETVLALR
ADHRLFSAAP VPLAHR
//
