ID A0A2V4XGH0_9FLAO Unreviewed; 531 AA.
AC A0A2V4XGH0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=DFQ11_10615 {ECO:0000313|EMBL:PYE80218.1};
OS Winogradskyella epiphytica.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Winogradskyella.
OX NCBI_TaxID=262005 {ECO:0000313|EMBL:PYE80218.1, ECO:0000313|Proteomes:UP000248054};
RN [1] {ECO:0000313|EMBL:PYE80218.1, ECO:0000313|Proteomes:UP000248054}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7945 {ECO:0000313|EMBL:PYE80218.1,
RC ECO:0000313|Proteomes:UP000248054};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PYE80218.1}.
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DR EMBL; QJTD01000006; PYE80218.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V4XGH0; -.
DR OrthoDB; 9767858at2; -.
DR Proteomes; UP000248054; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR Pfam; PF04675; DNA_ligase_A_N; 1.
DR SUPFAM; SSF117018; ATP-dependent DNA ligase DNA-binding domain; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:PYE80218.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000248054}.
FT DOMAIN 303..435
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 531 AA; 61464 MW; 99D2BD09E697D643 CRC64;
MRNFADLIRK LDSTTKTTLK VKALAKFFEN ASDEDRVWTI AILSHRRPPR PVNTTLLRKW
ASELSNIPLW LFEESYHIVG DLAETIALVI PNTESHSDKS LSEYLSEMIA LKAEDDDFKK
TYVTDHWRQL NYYERFVFTK LITGGFRIGV SQKLMTRALS QTTGIDEDIL AYKLMGKWDP
NTISFEDLVL KEKASDFLSK PYPFYLAYGL ETAAADLGAI EDWSIEHKWD GIRSQTIIRE
DHLFVWSRGE ELVTDKYPEF HPFATEIPNG TVLDGEILPF PDKAIGTFKD LQTRIGRKTL
SKALLEKTPV ILKVYDLLEW KGDDLRQQPF VKRRAILKDL MSSLSSKDLP IYLSEIVECQ
SWDEVAKERD RAREMRSEGL MIKRKDSTYQ VGRKKGDWWK WKTDPLTIDA VLTYAMRGHG
RRSNLFTDYT FALWNANGEE LVTFAKAYSG LTDAEFRKVD AWIKKNTIER FGPVRSVTPK
LVFEIAFEGI AKSSRHKSGY ATRFPRILRW RQDKKIEEAN SLQDLETLIP V
//
