ID A0A2V5IFE2_9EURO Unreviewed; 584 AA.
AC A0A2V5IFE2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Nuclear architecture-related protein 1 {ECO:0000256|ARBA:ARBA00031269};
GN ORFNames=BP00DRAFT_362761 {ECO:0000313|EMBL:PYI35475.1};
OS Aspergillus indologenus CBS 114.80.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1450541 {ECO:0000313|EMBL:PYI35475.1, ECO:0000313|Proteomes:UP000248817};
RN [1] {ECO:0000313|EMBL:PYI35475.1, ECO:0000313|Proteomes:UP000248817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114.80 {ECO:0000313|EMBL:PYI35475.1,
RC ECO:0000313|Proteomes:UP000248817};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the cytosolic Fe/S protein assembly machinery.
CC Required for maturation of extramitochondrial Fe/S proteins. May play a
CC role in the transfer of pre-assembled Fe/S clusters to target
CC apoproteins. {ECO:0000256|ARBA:ARBA00025099}.
CC -!- SIMILARITY: Belongs to the NARF family.
CC {ECO:0000256|ARBA:ARBA00006596}.
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DR EMBL; KZ825469; PYI35475.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V5IFE2; -.
DR Proteomes; UP000248817; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1780; -; 1.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR PANTHER; PTHR11615:SF258; CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR CG17683-RELATED; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 110..463
FT /note="Iron hydrogenase large subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02906"
FT REGION 29..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 584 AA; 62678 MW; 3CD4D00ECBA6D06D CRC64;
MSAILSADDL NDFISPGVAC IKPVETLPKK EESNSDNPYE VTKEDKVEPE NLPPAQISLT
DCLACSGCVT SAEAVLISLQ SHAEVLNTLD TYPELSLSGV DAQDGESRIF VASVSPQVRA
SLAATYGIAE KDAENMYHQF LSGPQGLRAG GAKNSGFTWV VDTNVMRDAV LSLTADEVSD
SLAATSDTTG SSSPKRPILS SACPGWICYA EKTHPFILPH LSRLKSPQAL TGTFLKTVLS
KSLGIPTSRI WHLAIMPCFD KKLEASREEL TDAAWSPSAA ESTTPVRDVD CVITTRELLS
LASSRGISLP SLPLKPTSQP QFPDPVLNDF LFSKGNSAQN ATTGTSGGYL YHVLTYFQSR
NPGSEIEIQR GRNADVVEYF LMSPERQPIM KAARYYGFRN IQNLVRKLKP ARVSRLPGAR
TANGAMGGSR RQPMGRNAAS GGSGSDYAYV EVMACPGGCT NGGGQIRIED ARDATSAQTE
TSGEAPKPSP HEQRAWLARV DEAYYSAESD SEGEVNPQSQ PLSLAEQEAR VHNALNHWAT
FMGVPLSKLA YTTYREVESD VGKPQGPPDA ARVVELAGKI GGGW
//
