ID   A0A2V5JIC9_9EURO        Unreviewed;      1058 AA.
AC   A0A2V5JIC9;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=NRPS-like enzyme {ECO:0000313|EMBL:PYI36626.1};
GN   ORFNames=BP00DRAFT_469446 {ECO:0000313|EMBL:PYI36626.1};
OS   Aspergillus indologenus CBS 114.80.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1450541 {ECO:0000313|EMBL:PYI36626.1, ECO:0000313|Proteomes:UP000248817};
RN   [1] {ECO:0000313|EMBL:PYI36626.1, ECO:0000313|Proteomes:UP000248817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 114.80 {ECO:0000313|EMBL:PYI36626.1,
RC   ECO:0000313|Proteomes:UP000248817};
RG   DOE Joint Genome Institute;
RA   Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA   Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA   Salamov A., Henrissat B., Wiebenga A., De vries R.P., Grigoriev I.V.,
RA   Mortensen U.H., Andersen M.R., Baker S.E.;
RT   "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT   speciation.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KZ825464; PYI36626.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2V5JIC9; -.
DR   Proteomes; UP000248817; Unassembled WGS sequence.
DR   GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR   GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR013120; Far_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   PANTHER; PTHR43439:SF2; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR   PANTHER; PTHR43439; PHENYLACETATE-COENZYME A LIGASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF07993; NAD_binding_4; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
FT   DOMAIN          46..355
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          571..641
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|Pfam:PF00550"
FT   DOMAIN          692..934
FT                   /note="Thioester reductase (TE)"
FT                   /evidence="ECO:0000259|Pfam:PF07993"
SQ   SEQUENCE   1058 AA;  117767 MW;  2A7F4CC7AC999FD0 CRC64;
     MVGVVNSAPE GFNAPRRLLV TQVDTIAKHS PNRRFGLIPN GTEVDQGFRE VTFRDLSQAV
     NAMSWWIDDT LGKPQSGEKI AYLGNNDVRY IIFMLACHKT GYTIFLPSTR LSDEAYNRVL
     MDTKCTHLLF SREKSPIASR LRTLDWKMQF QEVPSVADIL GNGSGTSHFE FSKTYDEVVD
     QIAFIIHSSG TTGMPKPVPL THGFLGTIDF AALIPMPPGR SSAFFNDLAS DDPKPNDLVL
     SSTPYFHLMG LTSFFESIFH NIPFVASPER LLSVGFLIDL IRHTKPTVTI LPPSILEDMS
     YSDEALRCLS TLKFVCYGGA PLAPEVGEKL ARYTQLRSAI GSSEMGIICS MVPEGENTWG
     YFEWNPLYQV DMQLIGDGLY ELVIPRVEYS LVMHGIFHTF PELKEYRSKD LYTRHPTNPK
     LWKYHGRYDD VIVLSNGEKL NPISLEKIVE GHPSVHRALL IGQRRFQTCL LIEPDFDKVA
     TPVDEKGLIS MIWPVVQAAN KTVPDYGQIA KTMIRLSSRE KPFRLTAKGT TQRHAVNKDY
     AEEIEEIYAA QDRELAMDLP SAITPDTVCG YLQNVICKLT GRQSINPSDD LYSRGLDSLQ
     AIQLSKILKN SVSSYNPELN TENLNVQQIY AHPTAEGLAN LLLGILDEPS SPIATVSRSD
     KIAQLISKYT NDLHIRESDV LPQLPALSTV ILTGSTGSLG SYILDDLLRK PQVAKVYCFN
     RSEDSLTRQR EGFQEKGLQT SPLDNPNKVE FLHVQFGETH FGLSDRQYTE LLDTVDVIIH
     NAWKVNFNHP VSSFEDPHLK GVREFVRFSQ DSRYRAHLAF VSSVSTIGAW KPSDGVPAIP
     EVPMETADAT LEQGYGESKY IGESICVEAS KKAGVPTSIL RVGQIAGPDT RLGAWNPHEW
     LPSLIKTSKA TGKVPSDLGG YPIDWVSVDT LARIVNELVL GRRASLGETR NAVFHLVNPS
     RTTWAALIPA IQERYPVQPV PLVDWVADLE TIQDPSDCDV QEKPALKLLA FFHGLADNAD
     VLSADISVER TRKGSETMAS LGPVSPAQMA NWLNQWNF
//