ID A0A2W1BMK9_HELAM Unreviewed; 138 AA.
AC A0A2W1BMK9;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Histone H2A {ECO:0000256|RuleBase:RU003767};
GN Name=HaOG204912 {ECO:0000313|EMBL:PZC76168.1};
GN ORFNames=B5X24_HaOG204912 {ECO:0000313|EMBL:PZC76168.1};
OS Helicoverpa armigera (Cotton bollworm) (Heliothis armigera).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC Noctuidae; Heliothinae; Helicoverpa.
OX NCBI_TaxID=29058 {ECO:0000313|EMBL:PZC76168.1, ECO:0000313|Proteomes:UP000249218};
RN [1] {ECO:0000313|EMBL:PZC76168.1, ECO:0000313|Proteomes:UP000249218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Harm_GR_Male_#8 {ECO:0000313|EMBL:PZC76168.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PZC76168.1};
RX PubMed=28756777; DOI=10.1186/s12915-017-0402-6;
RA Pearce S.L., Clarke D.F., East P.D., Elfekih S., Gordon K.H., Jermiin L.S.,
RA McGaughran A., Oakeshott J.G., Papanikolaou A., Perera O.P., Rane R.V.,
RA Richards S., Tay W.T., Walsh T.K., Anderson A., Anderson C.J., Asgari S.,
RA Board P.G., Bretschneider A., Campbell P.M., Chertemps T.,
RA Christeller J.T., Coppin C.W., Downes S.J., Duan G., Farnsworth C.A.,
RA Good R.T., Han L.B., Han Y.C., Hatje K., Horne I., Huang Y.P., Hughes D.S.,
RA Jacquin-Joly E., James W., Jhangiani S., Kollmar M., Kuwar S.S., Li S.,
RA Liu N.Y., Maibeche M.T., Miller J.R., Montagne N., Perry T., Qu J.,
RA Song S.V., Sutton G.G., Vogel H., Walenz B.P., Xu W., Zhang H.J., Zou Z.,
RA Batterham P., Edwards O.R., Feyereisen R., Gibbs R.A., Heckel D.G.,
RA McGrath A., Robin C., Scherer S.E., Worley K.C., Wu Y.D.;
RT "Genomic innovations, transcriptional plasticity and gene loss underlying
RT the evolution and divergence of two highly polyphagous and invasive
RT Helicoverpa pest species.";
RL BMC Biol. 15:63-63(2017).
CC -!- SUBUNIT: The nucleosome is a histone octamer containing two molecules
CC each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and
CC two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of
CC DNA. {ECO:0000256|RuleBase:RU003767}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|RuleBase:RU003767}.
CC -!- SIMILARITY: Belongs to the histone H2A family.
CC {ECO:0000256|RuleBase:RU003767}.
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DR EMBL; KZ149966; PZC76168.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2W1BMK9; -.
DR EnsemblMetazoa; XM_021337004.2; XP_021192679.1; LOC110377947.
DR OMA; QASTMSE; -.
DR OrthoDB; 3263617at2759; -.
DR Proteomes; UP000249218; Unassembled WGS sequence.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR CDD; cd00074; H2A; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR002119; Histone_H2A.
DR InterPro; IPR007125; Histone_H2A/H2B/H3.
DR InterPro; IPR032454; Histone_H2A_C.
DR PANTHER; PTHR23430; HISTONE H2A; 1.
DR PANTHER; PTHR23430:SF50; HISTONE H2A; 1.
DR Pfam; PF00125; Histone; 1.
DR Pfam; PF16211; Histone_H2A_C; 1.
DR PRINTS; PR00620; HISTONEH2A.
DR SMART; SM00414; H2A; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454, ECO:0000256|RuleBase:RU003767};
KW DNA-binding {ECO:0000256|RuleBase:RU003767};
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Nucleosome core {ECO:0000256|ARBA:ARBA00023269,
KW ECO:0000256|RuleBase:RU003767}; Nucleus {ECO:0000256|RuleBase:RU003767};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000249218}.
FT DOMAIN 16..91
FT /note="Histone H2A/H2B/H3"
FT /evidence="ECO:0000259|Pfam:PF00125"
FT DOMAIN 94..127
FT /note="Histone H2A C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16211"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 138 AA; 15278 MW; D5CE7EFD9AF7DD89 CRC64;
MPIKEIEESP SRLRAKPKSR SRRAGITLPV GRIHRILKNG NYAPRIGGGA AVYMAAVLDY
LASELLELSA NAADDNNRSR ISPRHILLAV RNDDELNKML AGVTISEGGV MPHINRHLLP
KKTQMKSHQN TNTSSQEY
//
