ID A0A2W1EBH8_9PLEO Unreviewed; 573 AA.
AC A0A2W1EBH8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=MFS-1 domain containing protein {ECO:0000313|EMBL:KAI1520620.1};
DE SubName: Full=ProP, Permease major facilitator superfamily {ECO:0000313|EMBL:KAF7576834.1};
GN ORFNames=Ptr86124_000988 {ECO:0000313|EMBL:KAI1520620.1}, PtrM4_010740
GN {ECO:0000313|EMBL:KAF7576834.1}, PtrM4_03343
GN {ECO:0000313|EMBL:PWO16025.1};
OS Pyrenophora tritici-repentis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC Pyrenophora.
OX NCBI_TaxID=45151 {ECO:0000313|EMBL:KAF7576834.1, ECO:0000313|Proteomes:UP000245464};
RN [1] {ECO:0000313|EMBL:KAF7576834.1, ECO:0000313|Proteomes:UP000245464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M4 {ECO:0000313|EMBL:KAF7576834.1,
RC ECO:0000313|Proteomes:UP000245464};
RX PubMed=29685100; DOI=10.1186/s12864-018-4680-3;
RA Moolhuijzen P., See P.T., Hane J.K., Shi G., Liu Z., Oliver R.P.,
RA Moffat C.S.;
RT "Comparative genomics of the wheat fungal pathogen Pyrenophora tritici-
RT repentis reveals chromosomal variations and genome plasticity.";
RL BMC Genomics 19:279-279(2018).
RN [2] {ECO:0000313|EMBL:KAI1520620.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=86-124 {ECO:0000313|EMBL:KAI1520620.1};
RA Moolhuijzen P.M., Moffat C.S.;
RL Submitted (MAY-2021) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAI1520620.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=86-124 {ECO:0000313|EMBL:KAI1520620.1};
RA Moolhuijzen P., See P.T., Shi G., Powell H.R., Cockram J., Jorgensen L.N.,
RA Benslimane H., Strelkov S.E., Turner J., Liu Z., Moffat C.S.;
RT "A global pangenome for the wheat fungal pathogen Pyrenophora tritici-
RT repentis and prediction of effector protein structural homology.";
RL bioRxiv 0:0-0(2022).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF7576834.1}.
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DR EMBL; NQIK02000001; KAF7576834.1; -; Genomic_DNA.
DR EMBL; NRDI02000001; KAI1520620.1; -; Genomic_DNA.
DR EMBL; NQIK01000002; PWO16025.1; -; Genomic_DNA.
DR OMA; WFESFAI; -.
DR Proteomes; UP000245464; Unassembled WGS sequence.
DR Proteomes; UP000249757; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17323; MFS_Tpo1_MDR_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23502:SF23; FLUCONAZOLE RESISTANCE PROTEIN 1; 1.
DR PANTHER; PTHR23502; MAJOR FACILITATOR SUPERFAMILY; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 468..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 536..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 130..562
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 71..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 573 AA; 64351 MW; 8575C0E5C6BB9E4E CRC64;
MLDLIRDSAF GHCVRLVTRG KYLQYPEERD HDIWKKYVSH EKSGYAAYHG KTHPPEDNAE
EALRELTQAY DVRSRERHDS NTTAVGEGVN EASGVRVDPE KGKDLHVIDW YGPDDPQNPR
NWSRGKRYFV TFEICFLTFS VYIGSAIYTP GLMGVMQEFG VAQVPATLGL TLYVAGYGLG
PLLWSPMSEI PQIGRLWVYI GTLLVFVLFQ LPTVYSVNFG MLLAFRFLTG FFGSPALATG
GASIADMYRP KKQVYGMAVW GVGAVCGPVL GPLVGGFAVM AEGWKWTIWE LMWLSGICWV
FLFFFLPETS SPNILYRRTK RLRKLTGDDR FTCEPEMTAA EMTPKDVILM SLVKPITLNF
TEPMVFLLNL YIALIYGLLY IWFESFPLVF EGIYGFNLGL EGVAFLGILV GTFLAAGVLF
AWNYWYLEPQ FDDNGNIQPE KRLIPAMVGC FAVPICLFWF GWASRSDVHW IVPIIGSGFF
GVAAFTLFQA VLPYLSDAYP DSVASVLAGN DLMRSSFGAG FPLFANAMYQ RLGINWASSL
LAFLGIAFIP IPFALYKWGK QIRHKSKLAR KDI
//
