ID A0A2W1GHM5_9PLEO Unreviewed; 470 AA.
AC A0A2W1GHM5;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Na antiporter {ECO:0000313|EMBL:KAI1518368.1};
DE SubName: Full=NhaP, NhaP-type Na+-H+ and K+-H+ antiporter {ECO:0000313|EMBL:PWO17435.1};
GN ORFNames=Ptr86124_001496 {ECO:0000313|EMBL:KAI1518368.1}, PtrM4_00312
GN {ECO:0000313|EMBL:PWO17435.1}, PtrM4_058960
GN {ECO:0000313|EMBL:KAF7574273.1};
OS Pyrenophora tritici-repentis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC Pyrenophora.
OX NCBI_TaxID=45151 {ECO:0000313|EMBL:PWO17435.1};
RN [1] {ECO:0000313|EMBL:PWO17435.1, ECO:0000313|Proteomes:UP000245464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M4 {ECO:0000313|EMBL:PWO17435.1,
RC ECO:0000313|Proteomes:UP000245464};
RX PubMed=29685100; DOI=10.1186/s12864-018-4680-3;
RA Moolhuijzen P., See P.T., Hane J.K., Shi G., Liu Z., Oliver R.P.,
RA Moffat C.S.;
RT "Comparative genomics of the wheat fungal pathogen Pyrenophora tritici-
RT repentis reveals chromosomal variations and genome plasticity.";
RL BMC Genomics 19:279-279(2018).
RN [2] {ECO:0000313|EMBL:KAI1518368.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=86-124 {ECO:0000313|EMBL:KAI1518368.1};
RA Moolhuijzen P.M., Moffat C.S.;
RL Submitted (MAY-2021) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAI1518368.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=86-124 {ECO:0000313|EMBL:KAI1518368.1};
RA Moolhuijzen P., See P.T., Shi G., Powell H.R., Cockram J., Jorgensen L.N.,
RA Benslimane H., Strelkov S.E., Turner J., Liu Z., Moffat C.S.;
RT "A global pangenome for the wheat fungal pathogen Pyrenophora tritici-
RT repentis and prediction of effector protein structural homology.";
RL bioRxiv 0:0-0(2022).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWO17435.1}.
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DR EMBL; NQIK02000002; KAF7574273.1; -; Genomic_DNA.
DR EMBL; NRDI02000002; KAI1518368.1; -; Genomic_DNA.
DR EMBL; NQIK01000001; PWO17435.1; -; Genomic_DNA.
DR OMA; TFGWLIC; -.
DR Proteomes; UP000245464; Unassembled WGS sequence.
DR Proteomes; UP000249757; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015385; F:sodium:proton antiporter activity; IEA:InterPro.
DR GO; GO:0120029; P:proton export across plasma membrane; IEA:InterPro.
DR GO; GO:0042391; P:regulation of membrane potential; IEA:InterPro.
DR GO; GO:0036376; P:sodium ion export across plasma membrane; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR004712; Na+/H+_antiporter_fungi.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR31382; NA(+)/H(+) ANTIPORTER; 1.
DR PANTHER; PTHR31382:SF2; NA_H_EXCHANGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..428
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
FT REGION 448..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..463
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 470 AA; 52053 MW; F62C7E37CCF19536 CRC64;
MVWSQLEPTG PHVTYVFLSF FLILYALFSL MIRNRLHLSE PPLATLFGII IGPRALNILR
PYDWGFSDDI IQETTRLIVG IQCFAVGLEL PNGYLQKRWR ALLVLLGPVM TFGWLICAMF
IMLLFQTDFQ TAMTIAACLT PTDPVLAASV LSNSQFSTRV PRRIRDLLSA ESGCNDGVSF
PFLYIGLSLL LKSTAFGVFK KWFLITILYQ CVVGVLLGIA LGRVFNALYR FSHGREWMGR
ASYLAFYLLL AVFSIGLASV LGVDDFLVAF FAGRGFSHNQ ASPMAETSLP VIIDLLINSA
FFVFFGAMIP WQSFGALDGI TIPRLFALLA LILVFRRIPI VFSLYKMKML PLVKTTTEAL
FVGHFGPIGV GAIFLAIEAR AQLETGTSLP LPSPPEDLPM DRQRTVTMIW PMVCFIVLGS
TMVHGFSTLA LSIGGHFARK EGERAPLIGG EREGLHGMVH DGSDDEENDE
//
