ID A0A2W1GPB2_9PLEO Unreviewed; 705 AA.
AC A0A2W1GPB2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Carotenoid oxygenase {ECO:0000313|EMBL:KAF7564565.1, ECO:0000313|EMBL:KAI1511327.1};
GN ORFNames=Ptr86124_009731 {ECO:0000313|EMBL:KAI1511327.1}, PtrM4_039990
GN {ECO:0000313|EMBL:KAF7564565.1}, PtrM4_11147
GN {ECO:0000313|EMBL:PWO07928.1};
OS Pyrenophora tritici-repentis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC Pyrenophora.
OX NCBI_TaxID=45151 {ECO:0000313|EMBL:KAI1511327.1, ECO:0000313|Proteomes:UP000249757};
RN [1] {ECO:0000313|EMBL:KAF7564565.1, ECO:0000313|Proteomes:UP000245464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M4 {ECO:0000313|EMBL:KAF7564565.1,
RC ECO:0000313|Proteomes:UP000245464};
RX PubMed=29685100; DOI=10.1186/s12864-018-4680-3;
RA Moolhuijzen P., See P.T., Hane J.K., Shi G., Liu Z., Oliver R.P.,
RA Moffat C.S.;
RT "Comparative genomics of the wheat fungal pathogen Pyrenophora tritici-
RT repentis reveals chromosomal variations and genome plasticity.";
RL BMC Genomics 19:279-279(2018).
RN [2] {ECO:0000313|EMBL:KAI1511327.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=86-124 {ECO:0000313|EMBL:KAI1511327.1};
RA Moolhuijzen P.M., Moffat C.S.;
RL Submitted (MAY-2021) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAI1511327.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=86-124 {ECO:0000313|EMBL:KAI1511327.1};
RA Moolhuijzen P., See P.T., Shi G., Powell H.R., Cockram J., Jorgensen L.N.,
RA Benslimane H., Strelkov S.E., Turner J., Liu Z., Moffat C.S.;
RT "A global pangenome for the wheat fungal pathogen Pyrenophora tritici-
RT repentis and prediction of effector protein structural homology.";
RL bioRxiv 0:0-0(2022).
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAI1511327.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NQIK02000010; KAF7564565.1; -; Genomic_DNA.
DR EMBL; NRDI02000014; KAI1511327.1; -; Genomic_DNA.
DR EMBL; NQIK01000010; PWO07928.1; -; Genomic_DNA.
DR Proteomes; UP000245464; Unassembled WGS sequence.
DR Proteomes; UP000249757; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF89; CAROTENOID 9,10(9',10')-CLEAVAGE DIOXYGENASE 1; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT BINDING 237
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 294
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 357
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 663
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 705 AA; 78177 MW; 1F856F7139E56C2D CRC64;
MSQTGQPNDK SPRHPYLSGN FASVTSTCPP TPVTWSGHIP DELLGGMYVR NGGNPVTNDD
LGREAHWFDG DGMLSGVWFS RAHDAAAKPV VNFVNQFILT DVYLTAIQNP TLRTPILPSI
STLVNPASSL LFILWRILRT VLVVLYTHLS GSARAIKRIS VANTSILFHD GRALATCESG
PPMRIALPSL ETVGWFDGHE AEGEATPQDE TSSRDAQKEC FGGTGLLSWM NEWTTGHPKV
DTVTDELVLF HCNFVPPYVH YSLLPAKGNS KSKSEKEAIL NAAVPGCSGG RLMHDFGVSR
HHTVILDLPL SLTPLNLAKN KPIVVYEPEK PARFGVFPRR QPGLVRWFET RGCCIFHTAN
AWDEFDGSDD VVAVNLLACR LTSASLVFSA ANLPPPPHPN RESTTRNRPM SFFAKYDDED
HAKDPEKPFL DDTSPLLERN TSISHYDDSG PATIPNIPIS HDDEEQCRLY YYRFLLSPGS
TNTITHEFAL SAISFEFPTV SPLTEMSRAR YVYGCSTVIE SFGAALGKAT KIDVLVRIDV
QTLLARADDS APEAISGCVD NRNIDEVLAS KDANDPIKAF RLPPNHFGQE ARFVPRKATG
QGDVALAEED GYLLFYVFNE DQLDEEGECK PDARSELWVL DARDMQTVVC KVQLQTRIPY
GLHGNWFTEE DISRQRDVQT LRSETHHPSD SRWSHLQKSI ISYLG
//
