ID A0A2W1JLH3_9CYAN Unreviewed; 351 AA.
AC A0A2W1JLH3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Delta(12)-fatty-acid desaturase {ECO:0000313|EMBL:PZD74203.1};
DE EC=1.14.19.6 {ECO:0000313|EMBL:PZD74203.1};
GN Name=desA_2 {ECO:0000313|EMBL:PZD74203.1};
GN ORFNames=C1752_01257 {ECO:0000313|EMBL:PZD74203.1};
OS Acaryochloris thomasi RCC1774.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Acaryochloridales;
OC Acaryochloridaceae; Acaryochloris; Acaryochloris thomasi.
OX NCBI_TaxID=1764569 {ECO:0000313|EMBL:PZD74203.1, ECO:0000313|Proteomes:UP000248857};
RN [1] {ECO:0000313|EMBL:PZD74203.1, ECO:0000313|Proteomes:UP000248857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC1774 {ECO:0000313|EMBL:PZD74203.1,
RC ECO:0000313|Proteomes:UP000248857};
RX PubMed=29904088; DOI=10.1038/s41598-018-27542-7;
RA Partensky F., Six C., Ratin M., Garczarek L., Vaulot D., Probert I.,
RA Calteau A., Gourvil P., Marie D., Grebert T., Bouchier C., Le Panse S.,
RA Gachenot M., Rodriguez F., Garrido J.L.;
RT "A novel species of the marine cyanobacterium Acaryochloris with a unique
RT pigment content and lifestyle.";
RL Sci. Rep. 8:9142-9142(2018).
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC {ECO:0000256|ARBA:ARBA00009295}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZD74203.1}.
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DR EMBL; PQWO01000003; PZD74203.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2W1JLH3; -.
DR OrthoDB; 9769653at2; -.
DR Proteomes; UP000248857; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0102985; F:delta12-fatty-acid desaturase activity; IEA:UniProtKB-EC.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:0044255; P:cellular lipid metabolic process; IEA:UniProt.
DR CDD; cd03507; Delta12-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR32100:SF35; OMEGA-3 FATTY ACID DESATURASE FAT-1; 1.
DR PANTHER; PTHR32100; OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:PZD74203.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000248857};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 63..312
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
SQ SEQUENCE 351 AA; 40670 MW; 7C29F446D5BA8780 CRC64;
MTASLIKPES KLRSLDNPEV TMQKIIQSLP KACFEKNARK AWTEVVVTVL GVALGYAAIV
FSPWYLLPFA WFFTGTALTG FFVIGHDCAH RSFAKKRWVN DVVGHICMMP LIYPFHGWRI
MHNFHHVHTN ELDVDNAWRP FSTEEYDGCG PVVAGAYKVI RGRLWWIGSI IHWFNLHFDW
RQYDEKDQAD IKLSVAVVVL FGAIAFPTLI LTTGVWGFIK FWLLPWMGYH FWMSTFTLVH
HTAPDVAFKP TDEWNPAEAQ LVGSIHCDYP WWITFLCHDI NVHIPHHVST AIPSYNLRMA
HESLKENWGE YVCETKFDLE LIKTITDDCH LYEPEKAYQS FKEHQAKAAR S
//
