ID A0A2W1K4S7_9FLAO Unreviewed; 827 AA.
AC A0A2W1K4S7;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 11.
DE SubName: Full=Zinc-dependent metalloprotease {ECO:0000313|EMBL:PZD76514.1};
GN ORFNames=DNG35_11845 {ECO:0000313|EMBL:PZD76514.1};
OS Mesonia sp. K7.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Mesonia.
OX NCBI_TaxID=2218606 {ECO:0000313|EMBL:PZD76514.1, ECO:0000313|Proteomes:UP000249791};
RN [1] {ECO:0000313|EMBL:PZD76514.1, ECO:0000313|Proteomes:UP000249791}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K7 {ECO:0000313|EMBL:PZD76514.1,
RC ECO:0000313|Proteomes:UP000249791};
RA Lai Q., Shao Z.;
RT "Mesonia sp. K7 draft genome sequence.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZD76514.1}.
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DR EMBL; QKQV01000022; PZD76514.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2W1K4S7; -.
DR OrthoDB; 9776599at2; -.
DR Proteomes; UP000249791; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd04276; ZnMc_MMP_like_2; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR InterPro; IPR033413; DUF5117.
DR InterPro; IPR033428; DUF5118.
DR InterPro; IPR032534; EcxA_zinc-bd.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR034032; Zn_MMP-like_bac.
DR PANTHER; PTHR38478; PEPTIDASE M1A AND M12B; 1.
DR PANTHER; PTHR38478:SF1; ZINC DEPENDENT METALLOPROTEASE DOMAIN LIPOPROTEIN; 1.
DR Pfam; PF16313; DUF4953; 1.
DR Pfam; PF17148; DUF5117; 1.
DR Pfam; PF17162; DUF5118; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:PZD76514.1};
KW Metalloprotease {ECO:0000313|EMBL:PZD76514.1};
KW Protease {ECO:0000313|EMBL:PZD76514.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000249791};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..827
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016086735"
FT DOMAIN 44..92
FT /note="DUF5118"
FT /evidence="ECO:0000259|Pfam:PF17162"
FT DOMAIN 100..289
FT /note="DUF5117"
FT /evidence="ECO:0000259|Pfam:PF17148"
FT DOMAIN 425..730
FT /note="EcxA zinc-binding"
FT /evidence="ECO:0000259|Pfam:PF16313"
SQ SEQUENCE 827 AA; 95337 MW; C27068192537EA30 CRC64;
MRKSLPAKIS FMSLCLLLTS CAIFQKKKQP AVDKPQTEKK GDIQPYSKVI TKDAKTDEGL
FTVHQIKDKY FYEIPDSLLN KEMLMVTRIA KTATGIGFGG GKQNTQVLRW EKKNDKILLR
IVSHDIVASD SLPIHEAVVN SNFEPILYAF PVKAIKKDSI TTSSVIEVSD LFEKDVNTLG
LPHYRRKDYK ISRLDESRSF IDTIRSYPKN IEVRHVKTYQ AAEPPSNLAS GVISLEISNS
MILLPEVPMK RRYFDQRVGW FTTSQTDYGL DVQKSKKITY LDRWRLEVKE EDREKFLRGE
LVEPKKPIVY YVDRATPKKW VPYIKQGIED WQVAFEAAGF KNAIIAKDPP SVEEDPDWSP
EDVRYSVVRY LASPIPNANG PHVSDPRSGE ILESDINWYH NVMTLLRNWF FVQTSAINPT
AQSVEFDDEV MGRLIRFVSA HEVGHTLGLP HNMGSSSAYK VEDLRDPEFT KKYGTAPSIM
DYARFNYVAQ PEDGDVALMP NIGVYDKYAI EWGYRPILDK SAEAEKEILD QWILEHAGDP
LYRFGSQQSG STIDPSSQTE DLGDDAVLAS EYGIKNLKRI IPNLMEWTAE NGKDYEDLSD
MYTQVLSQYN RYMGHVTANI GGVYEIYKTS DQEGAVYTHV KREKQEKAMQ FLHDQLFETP
EWLLHQPIFE RIQFDGSVEN LRTYQVRTLN NLLDFGRMAR LLENETINKD AYGLLDMMTD
LRKGLFEELP QGKTIDIYRR NLQRAYVERL NYLMTEKQSP VPSRYRAWIN RSDINVEQSD
IRPVVRAELN QLKTDAQRAI GRTSDRMSKF HLQDLVKRIE LILDPRD
//
