ID A0A2W1L4U6_9BACL Unreviewed; 749 AA.
AC A0A2W1L4U6;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Metal-dependent phosphohydrolase {ECO:0000313|EMBL:PZD93933.1};
GN ORFNames=DNH61_20805 {ECO:0000313|EMBL:PZD93933.1};
OS Paenibacillus sambharensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1803190 {ECO:0000313|EMBL:PZD93933.1, ECO:0000313|Proteomes:UP000249522};
RN [1] {ECO:0000313|EMBL:PZD93933.1, ECO:0000313|Proteomes:UP000249522}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SMB1 {ECO:0000313|EMBL:PZD93933.1,
RC ECO:0000313|Proteomes:UP000249522};
RA Pinnaka A.K., Singh H., Kaur M.;
RT "Paenibacillus imtechensis sp. nov.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZD93933.1}.
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DR EMBL; QKRB01000055; PZD93933.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2W1L4U6; -.
DR OrthoDB; 9806952at2; -.
DR Proteomes; UP000249522; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:PZD93933.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000249522};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 301..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 473..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 526..687
FT /note="HD/PDEase"
FT /evidence="ECO:0000259|SMART:SM00471"
SQ SEQUENCE 749 AA; 84240 MW; A1148E1098945AD8 CRC64;
MSRNQTTNRA VSLPSKSTGW KHGAGARWLL LLLFVLLFYA SLSPHLIPRT YDIKLGTISD
REIVARKQWN DEKATIKAQE RAAENVEPKY SIVALRNEGL IEQIFGRVEQ LNAEDQVTFQ
NKVDIYRREI PERYVSFVNN FVRTNLNSDT YSATLLEEMA KNVKDQQYQI PEETYYKLPL
LSSKQIEEME AVGVDVVRKL MSEQLRDAET ARAKVAELVN TSALNDRTSR EIVAELARYA
IMPNKFYDKE ATEEARVQAK EDTQPVVIKE GDVVVKRGQL ITEEVYERLE GLGLLQDSKN
YWPHLGLLLL SLLFLLLIYF YLEQSGILSS GPDRKYNNAQ LLMLWLIFAL NLLTMSIISM
IQTIELSYIG YLAPAALGAI LIALLLDTHL AMVCSLLFAT IGSIMFNLDN DHLFDFRYGF
VIAVVSFAAI FAVHRASQRS TILKAGIMVS LFGTVSVLTL LMFGDALPRT ELIYAGSFAF
ASGLLTAVLV IGLMPFFEIS FGILSALKLV ELSNPNHPLL RKLLTETPGT YHHSVMVGNL
SEAAAEAIGA NGLLCRVGSF YHDIGKTKRP SYFIENQTNI ENPHDSIEPK LSKSIIIAHA
RDGVDMLKAH NIPKPIRDIA EQHHGTTCLK YFYHKAVKLA EAEGEEPDFT EDDFRYSGPK
AQSKEAAIVG IADCVEAAVR SLRNPTMEQI ETMIQKIIKN RLDDNQFNEC DLTMKELDSI
SQTLKETVVG IFHSRIEYPE DVKPKERLG
//
