ID A0A2W1Z2P3_9MICO Unreviewed; 491 AA.
AC A0A2W1Z2P3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DEI94_12875 {ECO:0000313|EMBL:PZF46159.1};
OS Curtobacterium sp. MCBD17_040.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Curtobacterium.
OX NCBI_TaxID=2175674 {ECO:0000313|EMBL:PZF46159.1};
RN [1] {ECO:0000313|EMBL:PZF46159.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCBD17_040 {ECO:0000313|EMBL:PZF46159.1};
RA Chase A.B., Gomez-Lunar Z., Lopez A.E., Li J., Allison S.D., Martiny A.C.,
RA Martiny J.B.H.;
RT "Emergence of Soil Bacterial Ecotypes Along a Climate Gradient.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZF46159.1}.
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DR EMBL; QKTL01000015; PZF46159.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2W1Z2P3; -.
DR OrthoDB; 9786919at2; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR45436:SF5; SENSOR HISTIDINE KINASE TRCS; 1.
DR PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:PZF46159.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 160..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 184..246
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 261..475
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 491 AA; 51440 MW; 47B4D0976C879D3E CRC64;
MTLRRRLVLS IVALVVAVSA VIGAGSIIAL ATIQTTSIDS QIEHATDRAQ SHLNQGGGGF
GGAPPDDLAR PAGQAAGTLT AVYLNGNRVF STIIQESGSI KQLTAGQAQT LAQATVGNGA
QTVHLGGSVG DYRVAAVATT NGVLVVGLPM APVYASIWNL IWVVVVVMVV ALVAASLVAT
YAVRRSLRPL ERVAETATTV ARLPLVRGDQ LADVRVPQQD TDPRTEVGRV GTAFNRMLGH
IGDAMRAREA SEDKVRQFVA DASHELRTPL ASIRGYAELT RRMSVDLPDD VVYAMSRVEA
ESVRMTGMVE DLLLLARLDE GREIQFDDVD LTGLVLDAVN DAHAASPGHL IDVDVPDEPV
VVLGDAARLH QVVVNLVTNA RTHTPDGTRI TVGIATGPEG VDLTVRDTGQ GIDPAFLPKM
FERFARADSS RSRTAGSTGL GLAIVDAVVQ AHGGVVSVRS VPGDTVFTVR LPAVPSSPDD
LRRSGVAASG A
//
