ID A0A2W2ABG7_9BACT Unreviewed; 738 AA.
AC A0A2W2ABG7;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN Name=recQ {ECO:0000313|EMBL:PZF70962.1};
GN ORFNames=DN068_20825 {ECO:0000313|EMBL:PZF70962.1};
OS Taibaiella soli.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Taibaiella.
OX NCBI_TaxID=1649169 {ECO:0000313|EMBL:PZF70962.1, ECO:0000313|Proteomes:UP000248745};
RN [1] {ECO:0000313|EMBL:PZF70962.1, ECO:0000313|Proteomes:UP000248745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R1-15 {ECO:0000313|EMBL:PZF70962.1,
RC ECO:0000313|Proteomes:UP000248745};
RA Kim M.-K., Park S., Kim T.-S., Joung Y., Han J.-H., Kim S.B.;
RT "Mucibacter soli gen. nov., sp. nov., a new member of the family
RT Chitinophagaceae producing mucin.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZF70962.1}.
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DR EMBL; QKTW01000028; PZF70962.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2W2ABG7; -.
DR OrthoDB; 9763310at2; -.
DR Proteomes; UP000248745; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.10.1390; ATP-dependent DNA helicase RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR048671; RecQ-1-like_HTH.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF21220; RecQ-1-like_HTH; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:PZF70962.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000248745}.
FT DOMAIN 31..203
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 227..376
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 540..620
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 738 AA; 84127 MW; 0DF22745EC15B454 CRC64;
MATAKSKINL KKSLHEHFGF EGFKGDQEKI IKSILSGQDT FVIMPTGGGK SLCYQLPALL
SDGIAIIVSP LIALMKNQVD LIRGYSSSDH IAHFLNSTLS KTQQKKVKSD ILEGHTKMLY
VAPETLTKQE NISFFSDINI SFVAVDEAHC ISEWGHDFRP EYRKLRDMIE EINPNLPIIA
LTATATPKVQ DDIVKNLSLR EPNVFVSSFN RPNLYYEIVP KGKKEQVLKH MVKYIHSMKG
KSGIIYTLNR KTTEELASTL QANGISAVAY HAGLDATTRA QRQDTFLMEE VDVIVATIAF
GMGIDKPDVR FVMHYNIPKS LENYYQETGR AGRDGLEGNC LLYYSYKDVQ KLEHLMRDKP
LSEREMGAQL ISETLAYAES GVCRRRLLLH YFGEEYKSEN CGKCDNCLNP KEKLEVRDST
KIVLDTVNEL DERFNIDYVV NIILGKSNPQ IQTFRHDKLK SFGAGLIMKM DANFWQSLIR
QMMLEGMIRK DIEEYGLLKM TEKGHKFLKK PYSIMVALNH NYEEVAAVQE EEEVALGAAA
TLDTRLFDML KDLRKQVAKE KGLPPFVIFL ENSLEDMATN YPTTLEELEK IQGVSKGKAL
RYGRKFVDLI AGYVEENEIV KPDDFVMKSV VNKSGMKVFI IQNIDKKIPL ETIAKNKGLN
LQDLLTEMET IVASGTKLNL DYCIEQELDE YEQEDIFDYF RASHDDNLDS AYEEFKDRDV
SIEQLQMMRI KFLSEFGN
//
