ID A0A2W2BP96_9ACTN Unreviewed; 1306 AA.
AC A0A2W2BP96;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=ATP-dependent RNA helicase HrpA {ECO:0000313|EMBL:PZF88975.1};
GN ORFNames=C1I93_24470 {ECO:0000313|EMBL:PZF88975.1};
OS Micromonospora endophytica.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=515350 {ECO:0000313|EMBL:PZF88975.1, ECO:0000313|Proteomes:UP000248627};
RN [1] {ECO:0000313|EMBL:PZF88975.1, ECO:0000313|Proteomes:UP000248627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45430 {ECO:0000313|EMBL:PZF88975.1,
RC ECO:0000313|Proteomes:UP000248627};
RA Sahin N., Ay H., Saygin H.;
RT "Draft genome sequence of Jishengella endophytica.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZF88975.1}.
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DR EMBL; POTX01000224; PZF88975.1; -; Genomic_DNA.
DR OrthoDB; 9805617at2; -.
DR Proteomes; UP000248627; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd17989; DEXHc_HrpA; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:PZF88975.1};
KW Hydrolase {ECO:0000313|EMBL:PZF88975.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 76..239
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 276..451
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 1306 AA; 146119 MW; 73CD58E3376CDDEA CRC64;
MHRRLANLMF RDQRQLRRRL DGLRRLREPQ RRAAALAEIA TDIARAEARL ERRRGAVPTI
TYPAVLPVSE RKDDIAAAIR DHQVVIVAGE TGSGKTTQLP KICLELGRGI TGLIGHTQPR
RLAARTVADR IAEELGTELG DVIGYKVRFT DQVSEQSLVK LMTDGILLAE LQTDRMLRQY
DTLIIDEAHE RSLNIDFILG YLKQLLPRRP DLKVIITSAT IETDRFAKHF ADAEGEPAPV
VEVSGRTYPV EVRYRPLVEV VDTDEEETDE ENVRDQIQAI GEAVEELAAE GPGDILVFLS
GEREIRDTAD ALGKLVQNRR SLLGTEILPL YARLSVAEQH RVFAPHSGRR VVLATNVAET
SLTVPGIKYV VDPGTARISR YSQRLKVQRL PIEPVSQASA NQRKGRCGRT SDGICVRLYD
EQDFESRPEF TDPEILRTNL ASVILQMTAI GLGDIAAFPF IEPPDRRNIT DGVNLLHELG
ALDPAEADPA RRLTPLGRRL AQLPVDPRLA RMVLEGERNG CATEVMVIAA ALSIQDPRER
PVEKQAQADQ AHARFADAES DFVAFLSLWR YLREQQRALS SSAFRRMCKA EYLNYLRVRE
WQDIVSQLRQ VLRTPNADVP EEIDTPKVHQ SLLPGLLSHI GLKDAQKHEY LGARGAKFAV
FPGSALFKKP PRWVMAAELV ETSRLWGRVN GRIEPEWVEP LAQHLVKRSY SEPHWEKKQA
AVMAYEKVTL YGVPLVTSRK VNFGRIDPVL SRELFIRHAL VEGDWSTHHQ FWRDNQRLLA
EVAELENRAR RRDILVDDET IFQFYDERIP AEVVSGRHFD TWWKKTRRER PELLTFTREL
LVNSGRGGVD DTDYPDQWRA DGVALPLTYT FEPGTPADGV TVDIPLPLLN QVLAESFDWQ
VPGLREDLVV ALIRSLPKPV RRNFVPVPDF ARAALAAITP GEEPLLDALT RQLRRMTGVT
VPRDAWDLDK LPPHLRVTFR VLGDDDKPVA EGKDLPALQR RLKAEVRQVV AAAAPDLART
GLTGWDIGAL PRTIEQVRAG YQVTAYPALV DEGTAVGVKV FDSPAEQEAA HWAGTRRLLR
LTVPSPAKFL QGRLSNEAKL ALSRNPHGGV QALIEDTAGA AIDKLIADAG GPAWDAEGFA
ALRDAVRADL VDTVVVVMDR VRAVLAAAYA VQQRLGATKN LAVVAALADI RNQLTGLVHA
GFITETGYAR LPDLLRYLTA IERRLDRLPG NPARDKSQQD RVATVQREYD EMLAALPPAR
RNSAAVRQIR WMIEELRVNV FAQALGTPYP VSEQRIYRAM DDAESP
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