ID A0A2W2C3M6_9ACTN Unreviewed; 704 AA.
AC A0A2W2C3M6;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=cellulase {ECO:0000256|ARBA:ARBA00012601};
DE EC=3.2.1.4 {ECO:0000256|ARBA:ARBA00012601};
GN ORFNames=C1I93_19515 {ECO:0000313|EMBL:PZF92410.1}, Jiend_09440
GN {ECO:0000313|EMBL:BCJ57522.1};
OS Micromonospora endophytica.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=515350 {ECO:0000313|EMBL:PZF92410.1, ECO:0000313|Proteomes:UP000248627};
RN [1] {ECO:0000313|EMBL:PZF92410.1, ECO:0000313|Proteomes:UP000248627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45430 {ECO:0000313|EMBL:PZF92410.1,
RC ECO:0000313|Proteomes:UP000248627};
RA Sahin N., Ay H., Saygin H.;
RT "Draft genome sequence of Jishengella endophytica.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BCJ57522.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 109090 {ECO:0000313|EMBL:BCJ57522.1};
RA Komaki H., Tamura T.;
RT "Whole genome shotgun sequence of Jishengella endophytica NBRC 109090.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000966};
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DR EMBL; AP023358; BCJ57522.1; -; Genomic_DNA.
DR EMBL; POTX01000142; PZF92410.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2W2C3M6; -.
DR KEGG; meno:Jiend_09440; -.
DR OrthoDB; 9800955at2; -.
DR Proteomes; UP000248627; Unassembled WGS sequence.
DR Proteomes; UP000682317; Chromosome.
DR GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR GO; GO:0030247; F:polysaccharide binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.40.290; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR005102; Carbo-bd_X2.
DR InterPro; IPR001919; CBD2.
DR InterPro; IPR008965; CBM2/CBM3_carb-bd_dom_sf.
DR InterPro; IPR012291; CBM2_carb-bd_dom_sf.
DR InterPro; IPR040946; CBM46.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR31297:SF17; ENDOGLUCANASE; 1.
DR PANTHER; PTHR31297; GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B; 1.
DR Pfam; PF18448; CBM46; 1.
DR Pfam; PF00553; CBM_2; 1.
DR Pfam; PF03442; CBM_X2; 1.
DR Pfam; PF00150; Cellulase; 1.
DR SMART; SM00637; CBD_II; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49384; Carbohydrate-binding domain; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS51173; CBM2; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 36..145
FT /note="CBM2"
FT /evidence="ECO:0000259|PROSITE:PS51173"
FT REGION 142..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..175
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 704 AA; 76248 MW; 633C730ED8441CA4 CRC64;
MAGLSGTLRR TRWRFGLITS GIAVLLAGVG LINAGAAQAA AGCRVVYSAP SQWQGGFTAN
VDLTNLGDAL NGWRLTWTFP SGQRVTQAWN ATVAQSGNDV TASNLSYNAA LGTNQSVSFG
FNGSWTGANT APTSFALNGV TCTGSVGPST PPTSTPPPTT PVPTTPPPTT PPPAGDPMAY
VASMQPGWNL GNTFDAVGDD ETAWGNPRVT QAQLDAVRAQ GFNSIRIPVT WTNHHGPAPS
YTIDAAWLNR VKEVVGWALE DGFYVMINLH HDSWQWINTM PTDRTNVLNR YNALWTQIAA
AFRDASPRLH FESVNEPQFA NSSGDAQNAQ LLHELNVNFH RIVRASGGNN ATRMLVLPTL
HTSSEQARIN ELTTTINQLN DRNLIATVHF YGYWPFSVNV AGGTRFDATT QQDLTDAFDR
VHNAFVTRGI PVVIGEYGLL GFDRHTGTIQ QGEKLKFFEF LGYYAKARKL TTQLWDNGQH
FNRTTFQWKD AELFAQIKSS WTTRSGTASS DQVYVPRTGS ITAKALTLNL NGTTFQGLRQ
GTTNLTQGTD YTVSGNQLTL TASALTRLVG NRAYGVNATL QARFSTGVPW RIDVISYDPP
VLSNATGSTA SFAIPTQFRG DQLATMEAKY ADGSNAGPHD WTPFKEFDVA FAPDYPGNRI
TLTDTFFGAV RDNAPVTLTF HFWSGAQLTY RVTKSGGNVT GVTG
//
