ID A0A2W2CWB5_9ACTN Unreviewed; 1044 AA.
AC A0A2W2CWB5;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=AfsR family transcriptional regulator {ECO:0000313|EMBL:PZG02803.1};
GN ORFNames=C1I99_00985 {ECO:0000313|EMBL:PZG02803.1};
OS Micromonospora deserti.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=2070366 {ECO:0000313|EMBL:PZG02803.1, ECO:0000313|Proteomes:UP000248749};
RN [1] {ECO:0000313|EMBL:PZG02803.1, ECO:0000313|Proteomes:UP000248749}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=13K206 {ECO:0000313|EMBL:PZG02803.1,
RC ECO:0000313|Proteomes:UP000248749};
RA Sahin N., Saygin H., Ay H.;
RT "Draft genome sequence of Salinispora sp. 13K206.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZG02803.1}.
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DR EMBL; POUB01000004; PZG02803.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2W2CWB5; -.
DR OrthoDB; 7628974at2; -.
DR Proteomes; UP000248749; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 3.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 7.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50005; TPR; 4.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000248749};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 1..83
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT REPEAT 737..770
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 777..810
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 897..930
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 977..1010
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DNA_BIND 1..83
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 238..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1044 AA; 112365 MW; 024E72E516E6A1B3 CRC64;
MAYGADGPVG LGPARQRTLL AALLLEPGGA VAFDQLVDRV WGERPPQRAR VTLHTYLSRL
RTVLGGAGGP ALVRRMRSYA LEVDPGAVDL HRFRAMASGA RRADDGRAAT LWGDALGLWR
GEPFAGLDSD WLRAVRAELE AERLAAALDR HDVLLRRGEH GRLVPELTAA AAAHPLDERL
AGQLMLALYH CGRQADALAH YRLLHDRLVE EVGSDPGPGL RELHRRILRH DAELAPAPLG
LGGRRVPTEP PDRGAGDPRH LNGGRAATSP PAATGLPRRP AQLPADVPDF TGRATDLRRL
DKLLDERLDS GTAPAVVITA IAGAAGVGKT ALAVHWANRM TDRFPDGQLY VNLRGYDPDQ
PMPAADALAR FLTALGVAGQ DIPLDVDERA AKYRSELAGH RMLILLDNAA SVAQVRPLLP
GSSSSLVVVT SRDRLAGLVA LHGAHRLDLD LLPAAEAVDL LRRLIGSRVE AEPEAAATLA
EQCARLPLAL RVAAELAASR PDSTLAELVA ELADRQTRLH LLDAGDPYAA VREVFSWSIH
HLSPDAVRTF RLVGLHPGPD LDPYAAAALT GTGLDQTRRT LELLTQANLV HRTGRGRYGM
HDLLRAYAAH LANDDETEQL RQAAQQRLLD YYLTTAVSAT DTLHPGEAHY RPEATASATL
IPDLSDPKAA RAWLDAERYC LVAVAAYGRA VGASSYVAGL ARALYRYLSD AHLTEMVAIN
DHAYHAAEQA GDHIGSAHAL RQLGTAYNRL SRYQAAVEHL QQALARFREA GDLVGEALTL
TSLGTVGYRL GNHDDAMDHN RRSIELSRQA GDRLAEAFAL NNLGVAEERV GRYADAGDHY
RQALAIFREI GARYCVATAL LNVANVELRQ GDYAPAATNL RQSLAILQPL GGPITEAHAL
DTLGLLHLRL GEPEEATGYF RQALARFREA GERNGQAWSV NGLGEAAQLA GDATTALAHH
SEALAIATGA STRHQQARAH TGLGHAHKAL GDPDQAGRHY ERAYAIYAEL GMPDAEDVRV
YLAPLAGSRR QEATGLRAFE VAEE
//
