ID A0A2W2D483_9ACTN Unreviewed; 313 AA.
AC A0A2W2D483;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=C1I93_26610 {ECO:0000313|EMBL:PZF87203.1}, Jiend_23580
GN {ECO:0000313|EMBL:BCJ58936.1};
OS Micromonospora endophytica.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=515350 {ECO:0000313|EMBL:PZF87203.1, ECO:0000313|Proteomes:UP000248627};
RN [1] {ECO:0000313|EMBL:PZF87203.1, ECO:0000313|Proteomes:UP000248627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45430 {ECO:0000313|EMBL:PZF87203.1,
RC ECO:0000313|Proteomes:UP000248627};
RA Sahin N., Ay H., Saygin H.;
RT "Draft genome sequence of Jishengella endophytica.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BCJ58936.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 109090 {ECO:0000313|EMBL:BCJ58936.1};
RA Komaki H., Tamura T.;
RT "Whole genome shotgun sequence of Jishengella endophytica NBRC 109090.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR EMBL; AP023358; BCJ58936.1; -; Genomic_DNA.
DR EMBL; POTX01000277; PZF87203.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2W2D483; -.
DR KEGG; meno:Jiend_23580; -.
DR OrthoDB; 9802472at2; -.
DR Proteomes; UP000248627; Unassembled WGS sequence.
DR Proteomes; UP000682317; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd07906; Adenylation_DNA_ligase_LigD_LigC; 1.
DR CDD; cd07971; OBF_DNA_ligase_LigD; 1.
DR Gene3D; 3.30.1490.70; -; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR014146; LigD_ligase_dom.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR02779; NHEJ_ligase_lig; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:PZF87203.1}.
FT DOMAIN 107..240
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 313 AA; 33692 MW; BC86C559113DCB4F CRC64;
MPGAPLKPML AMTGPLPAGG GWAYEFKWDG VRALADIAAG RQRLYARSGA EITTAYPELI
PLAEQVDDAL LDGEVVLFDQ AGQPSFTALA ERMHVRNPAK AARLAATVPV TYMIFDLLRL
RGTDLTGWPY ARRRDTLDEL GLGAARWAVP PVFADGPATY AAAGEHGLEG VMAKRRDSAY
RPGVRSPDWV KVKLEVTGDF VVGGWRPGAR KIGGLLVGVP GAGGRLVYRG RVGGGIGAAL
ERELLRELEP LRTAASPFAG DVPRADARAA IWVTPQVVVE VKYGQRTPDG RLRFPRILRL
RPDKPAEEVD DAS
//
