ID   A0A2W2D8L7_9ACTN        Unreviewed;       755 AA.
AC   A0A2W2D8L7;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Alpha-L-fucosidase {ECO:0000313|EMBL:PZG00199.1};
GN   ORFNames=C1I93_03360 {ECO:0000313|EMBL:PZG00199.1}, Jiend_57990
GN   {ECO:0000313|EMBL:BCJ62377.1};
OS   Micromonospora endophytica.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=515350 {ECO:0000313|EMBL:PZG00199.1, ECO:0000313|Proteomes:UP000248627};
RN   [1] {ECO:0000313|EMBL:PZG00199.1, ECO:0000313|Proteomes:UP000248627}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45430 {ECO:0000313|EMBL:PZG00199.1,
RC   ECO:0000313|Proteomes:UP000248627};
RA   Sahin N., Ay H., Saygin H.;
RT   "Draft genome sequence of Jishengella endophytica.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:BCJ62377.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NBRC 109090 {ECO:0000313|EMBL:BCJ62377.1};
RA   Komaki H., Tamura T.;
RT   "Whole genome shotgun sequence of Jishengella endophytica NBRC 109090.";
RL   Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC       1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC       carbohydrate moieties of glycoproteins.
CC       {ECO:0000256|ARBA:ARBA00004071}.
CC   -!- SIMILARITY: Belongs to the beta/gamma-crystallin family.
CC       {ECO:0000256|ARBA:ARBA00009646}.
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DR   EMBL; AP023358; BCJ62377.1; -; Genomic_DNA.
DR   EMBL; POTX01000012; PZG00199.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2W2D8L7; -.
DR   KEGG; meno:Jiend_57990; -.
DR   Proteomes; UP000248627; Unassembled WGS sequence.
DR   Proteomes; UP000682317; Chromosome.
DR   GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR   GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR   CDD; cd00161; RICIN; 1.
DR   Gene3D; 2.80.10.50; -; 1.
DR   Gene3D; 2.60.20.10; Crystallins; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR001064; Beta/gamma_crystallin.
DR   InterPro; IPR016286; FUC_metazoa-typ.
DR   InterPro; IPR011024; G_crystallin-like.
DR   InterPro; IPR000933; Glyco_hydro_29.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR035992; Ricin_B-like_lectins.
DR   InterPro; IPR000772; Ricin_B_lectin.
DR   InterPro; IPR006311; TAT_signal.
DR   PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR   PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR   Pfam; PF01120; Alpha_L_fucos; 1.
DR   Pfam; PF14200; RicinB_lectin_2; 2.
DR   PRINTS; PR00741; GLHYDRLASE29.
DR   SMART; SM00812; Alpha_L_fucos; 1.
DR   SMART; SM00458; RICIN; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49695; gamma-Crystallin-like; 1.
DR   SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR   PROSITE; PS50915; CRYSTALLIN_BETA_GAMMA; 1.
DR   PROSITE; PS50231; RICIN_B_LECTIN; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          576..616
FT                   /note="Beta/gamma crystallin 'Greek key'"
FT                   /evidence="ECO:0000259|PROSITE:PS50915"
SQ   SEQUENCE   755 AA;  82402 MW;  1A8AAF0FE77D6DA2 CRC64;
     MSRPPVSRRT LLTALGAGGA AAAVGVGAGG VIRPLPAHAA IPGPSNYTES WASVGQHPAA
     AEWFQDAKFG IYYHWGVFSV PAFANEWYPR NMYNAGSGEN NHHRNTYGEP SAWPYHNFIN
     GANDRSGRFV QFAPRLRSAG GNFDPNEWAQ LFVDAGAKFA GPVAEHHDGF SMWNSQVNEW
     NSVARGPRLD LLKLHTDAIR ARGLKVLVAM HHAFNFTGFY QWAPQQSDPS LRKLYGQLGT
     AAEEQLWYDK LREIIDQSQP DIIWQDFDLH RISEAQRLRF LAYYYNRAVA WDKEVVATYK
     DGLERGGAVY DYERGGPAEL REPYWLTDDS ISSSSWCYTV GIGYYTLNQM LHSLIDRVSK
     NGNMVLNIAP MADGTIPAGQ QTLLRSIGDY LRRFGESIYS TRAWTTFGEG PTRMGGGYFV
     APVAGNAQDI RFTRSKDNRV LYATILGWPG SSVNITTLSS NRINLSSLTG VQLLDNTAGS
     YVNLPNRTQD ASGLRITLPS ASAPFSAPAY VVKLTFNGPI PTLGGGTSVS PVVSVYQNTG
     YDSGANLSIG SYTAAQLQSA GIGLRSISSV RVTAGHQLVG YANDNFSGTS WTFNSDNSDL
     RNTGNNDAIA SLRVTFNPST YLRITNVTNG LALDSGGNVA SGSPLKQWTW DSNSNLQWQI
     VDLGTGYYRI VNRTNGMVID GFGQTGNGAA AQQAAWNGSN NQQWQITDQG NRRYRITNRG
     TGLVLDGGGQ VASGSTVKQW SWDGNTNLMW NITTA
//