ID   A0A2W2EGW6_9ACTN        Unreviewed;       302 AA.
AC   A0A2W2EGW6;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Flap endonuclease {ECO:0000313|EMBL:PZG12860.1};
GN   ORFNames=C1I95_24920 {ECO:0000313|EMBL:PZG12860.1};
OS   Micromonospora craterilacus.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=1655439 {ECO:0000313|EMBL:PZG12860.1, ECO:0000313|Proteomes:UP000248924};
RN   [1] {ECO:0000313|EMBL:PZG12860.1, ECO:0000313|Proteomes:UP000248924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA12 {ECO:0000313|EMBL:PZG12860.1,
RC   ECO:0000313|Proteomes:UP000248924};
RA   Sahin N., Ay H., Saygin H.;
RT   "Draft genome sequence of Jishengella sp. NA12.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PZG12860.1}.
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DR   EMBL; POTY01000195; PZG12860.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2W2EGW6; -.
DR   OrthoDB; 9806424at2; -.
DR   Proteomes; UP000248924; Unassembled WGS sequence.
DR   GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR   CDD; cd09898; H3TH_53EXO; 1.
DR   CDD; cd09859; PIN_53EXO; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR   InterPro; IPR002421; 5-3_exonuclease.
DR   InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR   InterPro; IPR020045; DNA_polI_H3TH.
DR   InterPro; IPR038969; FEN.
DR   InterPro; IPR008918; HhH2.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR   PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR   Pfam; PF01367; 5_3_exonuc; 1.
DR   Pfam; PF02739; 5_3_exonuc_N; 1.
DR   SMART; SM00475; 53EXOc; 1.
DR   SMART; SM00279; HhH2; 1.
DR   SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Endonuclease {ECO:0000313|EMBL:PZG12860.1};
KW   Hydrolase {ECO:0000313|EMBL:PZG12860.1};
KW   Nuclease {ECO:0000313|EMBL:PZG12860.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248924}.
FT   DOMAIN          1..266
FT                   /note="5'-3' exonuclease"
FT                   /evidence="ECO:0000259|SMART:SM00475"
SQ   SEQUENCE   302 AA;  32178 MW;  B382BD9DF45F402D CRC64;
     MLVDAPSLYF RAYFGIPESA AKTADGQPVN AVRGFLDMLA QLIRTRRPGR MVCAMDHDWR
     PDWRVALLPS YKAHRVAPEG GEVVPDTLTP QVPMILDVLD ALGITVVGAP GYEADDVLGT
     LSVTQPGPVE VVSGDRDLFQ LIDDARGVRL LYIGRGVAKL DDCDDAAVRA RYGVPADRYA
     EFAALRGDPS DGLPGVAGVG EKTAARLVDR YGDIAGILAA LEDPASGFAP GLRTKLAAAR
     DYLAVAPKVV RVALDVPLPP LPTELPVAPA DPDRLLDLAE RWNLAGSTRR LVDALSTRTP
     AS
//