ID   A0A2W2ETS0_9ACTN        Unreviewed;       605 AA.
AC   A0A2W2ETS0;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Vanomycin resistance protein VanB {ECO:0000313|EMBL:PZG15818.1};
GN   ORFNames=C1I95_18805 {ECO:0000313|EMBL:PZG15818.1};
OS   Micromonospora craterilacus.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=1655439 {ECO:0000313|EMBL:PZG15818.1, ECO:0000313|Proteomes:UP000248924};
RN   [1] {ECO:0000313|EMBL:PZG15818.1, ECO:0000313|Proteomes:UP000248924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA12 {ECO:0000313|EMBL:PZG15818.1,
RC   ECO:0000313|Proteomes:UP000248924};
RA   Sahin N., Ay H., Saygin H.;
RT   "Draft genome sequence of Jishengella sp. NA12.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PZG15818.1}.
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DR   EMBL; POTY01000117; PZG15818.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2W2ETS0; -.
DR   OrthoDB; 9813301at2; -.
DR   Proteomes; UP000248924; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007391; Vancomycin_resist_VanW.
DR   InterPro; IPR022029; YoaR-like_PG-bd.
DR   PANTHER; PTHR35788; EXPORTED PROTEIN-RELATED; 1.
DR   PANTHER; PTHR35788:SF1; EXPORTED PROTEIN-RELATED; 1.
DR   Pfam; PF12229; PG_binding_4; 1.
DR   Pfam; PF04294; VanW; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248924};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        50..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          241..358
FT                   /note="YoaR-like putative peptidoglycan binding"
FT                   /evidence="ECO:0000259|Pfam:PF12229"
FT   REGION          23..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   605 AA;  64620 MW;  8AD858FD9C180389 CRC64;
     MTLYGEERPP ADDRPTVQVA AVNWPVEEPV RPAPVPPSGG EPPRSRRFRL LLASGVATAV
     LGSVGAVAVW AYAGDVPRGT TVLGTELGGR SRTDAARELR AQLDRRAAEL TAPIQVRVGE
     RTAEINPADV GLTVDVDATV AAAAAANAHA VDRLVGSREV QPVVSVDVPK LEAALEKLVG
     AQGRKMTMPA ITFSGTTPKV RYPKPSLAVD PEHSAQVVKD GWLGGQPVTV PLVENHPATS
     ADDVDRMVAE LAKPAVAAPV KLTTDRGSVS IPPQAIAKGL RFKADKTGKL TPSVDVKQLR
     AALGNKLDTV EVAAKDARMT ISGGKPKVID GRAGQQVDTS DLGRDLLAVL PQGEGRTVSA
     KLKPVEPKLT AEKLAGLGIK EKVSSFTTNF TGGLSSPRSQ NIVTIANDVK GTVVLPGATF
     SLNGHTGERG YAQGYRDAPV ILDGKLVPGV GGGTSQFTTT LFNASYYAGL QDVEHKPHSY
     YFSRYPAVIE STIFWPNLDF KFRNNTEYGV LIDTSYTANS VTVTMWSTKI WDSVKTEYGP
     RRNITSPRTV YLEPGPRCIP ANGSQGFTQD AFRVIKKDGK VVKREKFTWT YDAEPRFICA
     KEPSS
//