ID   A0A2W2G8K8_9ACTN        Unreviewed;       557 AA.
AC   A0A2W2G8K8;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
DE   Flags: Fragment;
GN   ORFNames=C1I98_26630 {ECO:0000313|EMBL:PZG36595.1};
OS   Spongiactinospora gelatinilytica.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Spongiactinospora.
OX   NCBI_TaxID=2666298 {ECO:0000313|EMBL:PZG36595.1, ECO:0000313|Proteomes:UP000248544};
RN   [1] {ECO:0000313|EMBL:PZG36595.1, ECO:0000313|Proteomes:UP000248544}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=7K107 {ECO:0000313|EMBL:PZG36595.1,
RC   ECO:0000313|Proteomes:UP000248544};
RA   Sahin N., Saygin H., Ay H.;
RT   "Draft genome sequence of Sphaerisporangium sp. 7K107.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PZG36595.1}.
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DR   EMBL; POUA01000256; PZG36595.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2W2G8K8; -.
DR   Proteomes; UP000248544; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR   PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           28..557
FT                   /note="VWFA domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016045789"
FT   DOMAIN          37..222
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          538..557
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         557
FT                   /evidence="ECO:0000313|EMBL:PZG36595.1"
SQ   SEQUENCE   557 AA;  57681 MW;  36D83567E9B4E047 CRC64;
     MRLAIHRLTA ALITLTATAV LPPPATAHTS RAAELAPVML VLDASGSMAQ TSADGRSKMA
     AARRAVHTVV DGLPAAARVG LAVYGTGTGN TAADKPAGCR DVKILHEVGT PGAELVATAD
     RVEPRGYTPI GRALRAAADA LPTEGPRSIV LVSDGEDTCA PPDPCEVAEE LAGEGADLRV
     HTIGFEVDAA ARKQLSCVAR QTGGSYTDAA EAGDLAPALN RVTGIALRNY EPTGTPVTGG
     EGPGDAAPLR PGDHLDEIAP GQARHYAIDV PAGNTAWFTA TGVFPPAAPA RETLTLARYA
     PDGTRCAWSD TGHSATGDPV VPLARTWRVS ADPGEGGPCD RPGRFTLVVE RDPGPGEPAW
     LELKVGLEPP VTADPGPARD PEVAFAEPAG EGEPAKVTGG GSFTTAGTLD GSGRYSDTLY
     PGEYVFYRVR LGWGQGLAYR VRLPAGDAPG ARLLTKTSAY GPARALIAQS GILWYDGEAG
     RLPTDRDALA IRPVRYLNRE LTAARGQALP GWYYIAIKYG SRPDLPETAP PVEIALDVSV
     TGRTEPGPSY ATTAPES
//