ID   A0A2W2HAK4_9ACTN        Unreviewed;       667 AA.
AC   A0A2W2HAK4;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   13-SEP-2023, entry version 15.
DE   RecName: Full=MBL fold metallo-hydrolase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=C1I98_12040 {ECO:0000313|EMBL:PZG49045.1};
OS   Spongiactinospora gelatinilytica.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Spongiactinospora.
OX   NCBI_TaxID=2666298 {ECO:0000313|EMBL:PZG49045.1, ECO:0000313|Proteomes:UP000248544};
RN   [1] {ECO:0000313|EMBL:PZG49045.1, ECO:0000313|Proteomes:UP000248544}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=7K107 {ECO:0000313|EMBL:PZG49045.1,
RC   ECO:0000313|Proteomes:UP000248544};
RA   Sahin N., Saygin H., Ay H.;
RT   "Draft genome sequence of Sphaerisporangium sp. 7K107.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PZG49045.1}.
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DR   EMBL; POUA01000071; PZG49045.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2W2HAK4; -.
DR   Proteomes; UP000248544; Unassembled WGS sequence.
DR   CDD; cd16295; TTHA0252-CPSF-like_MBL-fold; 1.
DR   Gene3D; 3.40.50.10890; -; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR022712; Beta_Casp.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR011108; RMMBL.
DR   PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR   PANTHER; PTHR11203:SF37; INTEGRATOR COMPLEX SUBUNIT 11; 1.
DR   Pfam; PF10996; Beta-Casp; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   Pfam; PF07521; RMMBL; 1.
DR   SMART; SM01027; Beta-Casp; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          239..437
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
FT   DOMAIN          471..577
FT                   /note="Beta-Casp"
FT                   /evidence="ECO:0000259|SMART:SM01027"
FT   COILED          104..159
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   667 AA;  71809 MW;  E2743257E8008FCC CRC64;
     MSSDLLLPVL HAAAKVVLSR PALAEKGHDV ERFAADNREM LLDALVKVPE LRGRVRAELR
     IRRDQPDAQA LATLVLADDD EVVRAALRLS EHLVRESRTQ QVRLRRHQEK LSELRSRLER
     ANGRHEHTLT GLRTTSAALA DADKRAEELD IQVSALQRRL GDPRTAASSL LAALQGHSAT
     EPAALLERAA GAAGISSLEL VTAIQAIVSP PQEIAGDRVS VVRERALRVT PLGGDTEIGG
     SCVLVEAGGT RLLVDAGLRP GDPARPPRDI DRALTGPIDA AVVTHAHTDH CGYIPALVER
     FPELRVMATP ATVQLMPAMW ADSAKLMIRR ERTYRQWGAD GATALYGRAA VEEAAQRCEE
     VPYGRPRQVG EVTLELFPAG HILGAAGVVV RAGDQRVAIS GDISGFNQRT VDGYQIPESA
     READLLVLES TCCAETHGPR EGRVNDLVKA VGDVHAAGGR VLIPAFALGR AQEIALILQD
     RLPHVPVLLD GMAADVAAAF ERVTAEGPAP LRIFQGSVSR ADRPADLDRF VSGVVITTSG
     MMTGGPAVQW AARILPEPNG ALFLSGYQDE ESGGARLLRL AEDGAASLTL DDNGVERKVP
     IRARIEMMRL SAHADKRGLL DIADEVAARE VMLVHGFSAR QREFAKILSV RRHSSVASGV
     WGEQRQE
//