ID   A0A2W2K2Z2_9ACTN        Unreviewed;       366 AA.
AC   A0A2W2K2Z2;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Ion channel protein {ECO:0000313|EMBL:PZG92122.1};
GN   ORFNames=C1I97_29565 {ECO:0000313|EMBL:PZG92122.1};
OS   Streptomyces sp. NTH33.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1735453 {ECO:0000313|EMBL:PZG92122.1, ECO:0000313|Proteomes:UP000248559};
RN   [1] {ECO:0000313|EMBL:PZG92122.1, ECO:0000313|Proteomes:UP000248559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NTH33 {ECO:0000313|EMBL:PZG92122.1,
RC   ECO:0000313|Proteomes:UP000248559};
RA   Sahin N., Ay H., Saygin H.;
RT   "Draft genome sequence of Streptomyces sp. NTH33.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PZG92122.1}.
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DR   EMBL; POTZ01000430; PZG92122.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2W2K2Z2; -.
DR   OrthoDB; 9799090at2; -.
DR   Proteomes; UP000248559; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013099; K_chnl_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003148; RCK_N.
DR   PANTHER; PTHR43833:SF9; POTASSIUM CHANNEL PROTEIN 2-RELATED; 1.
DR   PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR   Pfam; PF07885; Ion_trans_2; 1.
DR   Pfam; PF02254; TrkA_N; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR   PROSITE; PS51201; RCK_N; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248559};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        103..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          145..270
FT                   /note="RCK N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51201"
SQ   SEQUENCE   366 AA;  39659 MW;  1587251554F71FA2 CRC64;
     MKLPGHDAIA RQAGEHLVTH RVKLPRKIVE RPIRQVGKRL SLALLVLCAT VAIVYADRGG
     YQDSGKDAPM DLIAAAYYAT VTLSTTGYGD ITPVSDSARL TNIFVITPLR VIFLIILVGT
     TLEVLTERTR EEWRLNRWRS TLRDHTIVVG FGTKGRSALR TVCAAGLKKQ QVVVVDPSSK
     VIDAATADGY AGVVGDATRS EVLKRAEVQR ARQIIVATQR DDTAVLVTLT ARQLNRAAKI
     VAAVREEENA PLLKQSGADA VVTSASAAGR LLGLSVLSPA ASVVLEDLIQ QGSGLDIVER
     PVIKAEVGQD PREMDDLVVS VLRGHRVLAY DDPTVRELQL TDRLITIVRT TPGTRVIPDT
     RPLPQD
//