ID   A0A2W2L4K1_9ACTN        Unreviewed;       277 AA.
AC   A0A2W2L4K1;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=HAD-IB family hydrolase {ECO:0000313|EMBL:PZG96258.1};
GN   ORFNames=C1I97_26420 {ECO:0000313|EMBL:PZG96258.1};
OS   Streptomyces sp. NTH33.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1735453 {ECO:0000313|EMBL:PZG96258.1, ECO:0000313|Proteomes:UP000248559};
RN   [1] {ECO:0000313|EMBL:PZG96258.1, ECO:0000313|Proteomes:UP000248559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NTH33 {ECO:0000313|EMBL:PZG96258.1,
RC   ECO:0000313|Proteomes:UP000248559};
RA   Sahin N., Ay H., Saygin H.;
RT   "Draft genome sequence of Streptomyces sp. NTH33.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily. SerB family.
CC       {ECO:0000256|ARBA:ARBA00009184}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PZG96258.1}.
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DR   EMBL; POTZ01000339; PZG96258.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2W2L4K1; -.
DR   OrthoDB; 25607at2; -.
DR   Proteomes; UP000248559; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd02612; HAD_PGPPase; 1.
DR   Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR   Gene3D; 1.20.1440.100; SG protein - dephosphorylation function; 1.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR006385; HAD_hydro_SerB1.
DR   InterPro; IPR023214; HAD_sf.
DR   NCBIfam; TIGR01488; HAD-SF-IB; 1.
DR   NCBIfam; TIGR01490; HAD-SF-IB-hyp1; 1.
DR   PANTHER; PTHR43344:SF22; PHOSPHATASE RV3661-RELATED; 1.
DR   PANTHER; PTHR43344; PHOSPHOSERINE PHOSPHATASE; 1.
DR   Pfam; PF12710; HAD; 1.
DR   SUPFAM; SSF56784; HAD-like; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:PZG96258.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248559};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        249..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   277 AA;  30307 MW;  5EEB22F77A9869AE CRC64;
     MLGGVENHSL PRTAAFFDLD KTVIAKSSTL TFSKSFYQGG LINRRAVLRT AYAQFVFLAG
     GADHDQMERM RKYLSALCRG WNVRQVKEIV AETLHDLIDP IIYDEAASLI EEHHTAGRDV
     VIVSTSGAEV VEPIGELLGA DRVMATRMVV GEDGCFTGEV EYYAYGPTKA EAIRELAASE
     GYDLTRCYAY SDSVTDLPML ESVGRPHAVN PDRALRREAV ARGWPILDFH RPVRLKQRLP
     AFSVPPRPAL VAAAAIGAAA ATAGLVWYAN RRRGAVA
//