ID   A0A2W2M5A4_9ACTN        Unreviewed;       410 AA.
AC   A0A2W2M5A4;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=FAD-dependent oxidoreductase {ECO:0000313|EMBL:PZH15997.1};
GN   ORFNames=C1I97_07210 {ECO:0000313|EMBL:PZH15997.1};
OS   Streptomyces sp. NTH33.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1735453 {ECO:0000313|EMBL:PZH15997.1, ECO:0000313|Proteomes:UP000248559};
RN   [1] {ECO:0000313|EMBL:PZH15997.1, ECO:0000313|Proteomes:UP000248559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NTH33 {ECO:0000313|EMBL:PZH15997.1,
RC   ECO:0000313|Proteomes:UP000248559};
RA   Sahin N., Ay H., Saygin H.;
RT   "Draft genome sequence of Streptomyces sp. NTH33.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PZH15997.1}.
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DR   EMBL; POTZ01000046; PZH15997.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2W2M5A4; -.
DR   OrthoDB; 1145at2; -.
DR   Proteomes; UP000248559; Unassembled WGS sequence.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.30.390.30; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR   InterPro; IPR028202; Reductase_C.
DR   PANTHER; PTHR43557; APOPTOSIS-INDUCING FACTOR 1; 1.
DR   PANTHER; PTHR43557:SF2; RIESKE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF14759; Reductase_C; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000248559}.
FT   DOMAIN          6..302
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
FT   DOMAIN          322..408
FT                   /note="Reductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14759"
SQ   SEQUENCE   410 AA;  44505 MW;  DBE48D991177F47D CRC64;
     MASATFVIVG ASLAGAKAAE ALRGHGFDGR ILLIGDEPDH PYERPPLSKG YLQGKQDRET
     IFVHPEQWYA EQAIDLRVDT TVTELDRDRR TVTLSGGERI GYDKLLLATG ASPRRLPVPG
     ADLDGVLYLR RVGDCERIQR TFQSASRIVF VGGGWIGLEV AAAAREADVD VTVLEADELP
     LLRVMGRQIA PVFADLHREH GVDLRLTAQV TEIIGENGTV AGVRLADGTR IDADAVVVGI
     GAVPNTQLAA EAGLNVDNGI IVDASLRTSD PDIHAAGDVA NAFHPMLGKH IRVEHWANAL
     HQPETAARSM LGEAASYDRV PYFFTDQYDL GMEYAGYAEP DSYDDVVVRG DLTSRQFIAF
     WTAQGRVLAG MNVNIWDVNE AIQHLVRSGT QVDRDRLADP DVPLEELATG
//