ID   A0A2W2M6A7_9ACTN        Unreviewed;       537 AA.
AC   A0A2W2M6A7;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Monooxygenase {ECO:0000313|EMBL:PZH18332.1};
GN   ORFNames=C1I97_04020 {ECO:0000313|EMBL:PZH18332.1};
OS   Streptomyces sp. NTH33.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1735453 {ECO:0000313|EMBL:PZH18332.1, ECO:0000313|Proteomes:UP000248559};
RN   [1] {ECO:0000313|EMBL:PZH18332.1, ECO:0000313|Proteomes:UP000248559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NTH33 {ECO:0000313|EMBL:PZH18332.1,
RC   ECO:0000313|Proteomes:UP000248559};
RA   Sahin N., Ay H., Saygin H.;
RT   "Draft genome sequence of Streptomyces sp. NTH33.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PZH18332.1}.
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DR   EMBL; POTZ01000022; PZH18332.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2W2M6A7; -.
DR   OrthoDB; 8670884at2; -.
DR   Proteomes; UP000248559; Unassembled WGS sequence.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.2450; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR002938; FAD-bd.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR43476; 3-(3-HYDROXY-PHENYL)PROPIONATE/3-HYDROXYCINNAMIC ACID HYDROXYLASE; 1.
DR   PANTHER; PTHR43476:SF3; FAD_BINDING_3 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01494; FAD_binding_3; 1.
DR   PRINTS; PR00420; RNGMNOXGNASE.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Monooxygenase {ECO:0000313|EMBL:PZH18332.1};
KW   Oxidoreductase {ECO:0000313|EMBL:PZH18332.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248559}.
FT   DOMAIN          5..336
FT                   /note="FAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01494"
FT   REGION          345..414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        345..379
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   537 AA;  58108 MW;  7402B114B78938B7 CRC64;
     MNKACDVLVV GAGPVGLTLA NLLGQQGIDV LVVEREHELI DYPRAVGIDD EALRAMQTAG
     LVDEVLPHTI PDQKIYMING DRMILSEVNP TTREFGWPRR NGFVQPLVDQ VLLAGLDRFP
     NAAVRFGAEV VDLSEDADGV VATLANGETV RALYVVAAEG GSSPTRKRLG ISFGGETRPT
     DGIVIDVAND PIGTPHAVFG GDPARSYASI ALPHGIRRWE FTLFENESEA DVDDDAFVFG
     LLAPHVPDPS RLDIIRRRVY RHHARIAGRF RHGRIFLAGD AAHVMPVVGG QGWNSGIRDA
     FNLGWKLASV VKGLATDGLL DTYETERLGH VTQMVAVSLQ MAKEMTDHDP QKAAERDRIA
     AGRTPEEREA QERQAFKPQP KFDRGVVVHT PLPTSKSLPD RDVPRLAGTV FPQPTATDAD
     GVEMLLDDAT GQGWRILAWN NDPTAFLSAP RRAALDRFGA RLVQVVPKAQ LPWARKQATA
     GVTVVGDLGG ESSLQAWFDA RPVGAVVVRP DHVIAAECLA QELDDVVARV LEAACAA
//