ID A0A2W2MD95_9ACTN Unreviewed; 186 AA.
AC A0A2W2MD95;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:PZH07931.1};
GN ORFNames=C1I97_17110 {ECO:0000313|EMBL:PZH07931.1};
OS Streptomyces sp. NTH33.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1735453 {ECO:0000313|EMBL:PZH07931.1, ECO:0000313|Proteomes:UP000248559};
RN [1] {ECO:0000313|EMBL:PZH07931.1, ECO:0000313|Proteomes:UP000248559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NTH33 {ECO:0000313|EMBL:PZH07931.1,
RC ECO:0000313|Proteomes:UP000248559};
RA Sahin N., Ay H., Saygin H.;
RT "Draft genome sequence of Streptomyces sp. NTH33.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZH07931.1}.
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DR EMBL; POTZ01000159; PZH07931.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2W2MD95; -.
DR OrthoDB; 2356263at2; -.
DR Proteomes; UP000248559; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR InterPro; IPR041583; TetR_C_31.
DR PANTHER; PTHR30055:SF259; HTH TETR-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR Pfam; PF17940; TetR_C_31; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000248559};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..61
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 24..43
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 186 AA; 20075 MW; F71204AEA2DC821A CRC64;
MGNREKLLEA ARQCLFTKGY ERTTVRDLAS AAGVSMAAIG YHFGSKEALL NQALFEALDS
GDQAFGPSAG DTDLGTLWRR LIEAFSVNKT FWIANLETVL RAQRDPELRE QVAAGLRQGR
SGMAREVTGT AETELSEATI RTVGSVQLAL VSGLMMQHLT DPESAPTADE VLAGLRALAT
YLPEET
//
