ID A0A2W2MZL6_9ACTN Unreviewed; 312 AA.
AC A0A2W2MZL6;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=ATP-dependent DNA ligase {ECO:0000313|EMBL:PZH02195.1};
GN ORFNames=C1I97_21485 {ECO:0000313|EMBL:PZH02195.1};
OS Streptomyces sp. NTH33.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1735453 {ECO:0000313|EMBL:PZH02195.1, ECO:0000313|Proteomes:UP000248559};
RN [1] {ECO:0000313|EMBL:PZH02195.1, ECO:0000313|Proteomes:UP000248559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NTH33 {ECO:0000313|EMBL:PZH02195.1,
RC ECO:0000313|Proteomes:UP000248559};
RA Sahin N., Ay H., Saygin H.;
RT "Draft genome sequence of Streptomyces sp. NTH33.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZH02195.1}.
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DR EMBL; POTZ01000233; PZH02195.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2W2MZL6; -.
DR OrthoDB; 4296267at2; -.
DR Proteomes; UP000248559; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 3.90.920.10; DNA primase, PRIM domain; 1.
DR InterPro; IPR014145; LigD_pol_dom.
DR NCBIfam; TIGR02778; ligD_pol; 1.
DR PANTHER; PTHR42705; BIFUNCTIONAL NON-HOMOLOGOUS END JOINING PROTEIN LIGD; 1.
DR PANTHER; PTHR42705:SF2; MULTIFUNCTIONAL NON-HOMOLOGOUS END JOINING DNA REPAIR PROTEIN LIGD; 1.
DR Pfam; PF21686; LigD_Prim-Pol; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:PZH02195.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000248559}.
FT DOMAIN 40..290
FT /note="DNA ligase D polymerase"
FT /evidence="ECO:0000259|Pfam:PF21686"
FT REGION 289..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 312 AA; 34604 MW; 3671AAB0ABDDDB79 CRC64;
MSGGTRTVRA GRRTVEVHRA DKVLFPGGDG GGDSAAKEYT KGDLVDYYRS VAPFMLPHLR
GRPLMLERHP DGLDGPAFMQ KNTPENYPDW ITRAEVAKED GTVTHTVCDD TATLVYLADQ
ACLTLHRWLS RTRDVERPDR MVFDLDPADD DFTSVREAAR LLKELLDELR LPSALMTTGS
RGLHVIVPLD GRHDFDEVRD FARDVAELLA AGHPGRLTTA ARKKDRGDRL YLDVQRNGYA
QTAVAPFTVR ARPGAPVAAP IAWDQLGDPD LGPRRWTIAD AVDQARTDPW AGVPRRGRAL
GPARRRLDSL RG
//
