ID A0A2W2N1M3_9ACTN Unreviewed; 369 AA.
AC A0A2W2N1M3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Daunorubicin biosynthesis sensory transduction protein DnrJ {ECO:0000313|EMBL:PZH20839.1};
GN ORFNames=C1I97_00925 {ECO:0000313|EMBL:PZH20839.1};
OS Streptomyces sp. NTH33.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1735453 {ECO:0000313|EMBL:PZH20839.1, ECO:0000313|Proteomes:UP000248559};
RN [1] {ECO:0000313|EMBL:PZH20839.1, ECO:0000313|Proteomes:UP000248559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NTH33 {ECO:0000313|EMBL:PZH20839.1,
RC ECO:0000313|Proteomes:UP000248559};
RA Sahin N., Ay H., Saygin H.;
RT "Draft genome sequence of Streptomyces sp. NTH33.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DegT/DnrJ/EryC1 family.
CC {ECO:0000256|RuleBase:RU004508}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZH20839.1}.
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DR EMBL; POTZ01000004; PZH20839.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2W2N1M3; -.
DR OrthoDB; 9804264at2; -.
DR Proteomes; UP000248559; Unassembled WGS sequence.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00616; AHBA_syn; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000653; DegT/StrS_aminotransferase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR30244:SF36; 3-OXO-GLUCOSE-6-PHOSPHATE:GLUTAMATE AMINOTRANSFERASE; 1.
DR PANTHER; PTHR30244; TRANSAMINASE; 1.
DR Pfam; PF01041; DegT_DnrJ_EryC1; 1.
DR PIRSF; PIRSF000390; PLP_StrS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR000390-2,
KW ECO:0000256|RuleBase:RU004508};
KW Reference proteome {ECO:0000313|Proteomes:UP000248559}.
FT ACT_SITE 186
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000390-1"
FT MOD_RES 186
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR000390-2"
SQ SEQUENCE 369 AA; 39907 MW; A7CF86A451E264FB CRC64;
MTTRVWDYLE EYAAERKDIL DAVETVFSSG RLVLGASTHG FEREFASYHG MPHCIGVDNG
TNAIKLALQA LGVRPGDEVV TVSNTAAPTV VAIDSVGAKP VFVDIDPDTY LMDTAQVAAA
VTARTRCLLP VHLYGQCVDL APLRTLADAH GLALLEDCAQ AHGARHDGVL AGTTGDAAAF
SFYPTKVLGA YGDGGAVLVR DDDTAGRLRR LRYYGMEERY YVVETPGHNA RLDEVQAEIL
RRKLPRLDAY VAARRAVAER YAEGLAGTDL ALPAIAPGND HVYYVYVVRH PERDRILQAL
REHDIDLNIS YPWPVHTMSG FAGLGVPAGS LPVTESLAGQ IFSLPMYPSL TPAVQDRVIG
VLREVLAAL
//
