ID   A0A2W7N604_9BACT        Unreviewed;       819 AA.
AC   A0A2W7N604;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=LX69_02231 {ECO:0000313|EMBL:PZX15143.1};
OS   Breznakibacter xylanolyticus.
OC   Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Marinilabiliaceae;
OC   Breznakibacter.
OX   NCBI_TaxID=990 {ECO:0000313|EMBL:PZX15143.1, ECO:0000313|Proteomes:UP000249239};
RN   [1] {ECO:0000313|EMBL:PZX15143.1, ECO:0000313|Proteomes:UP000249239}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 6779 {ECO:0000313|EMBL:PZX15143.1,
RC   ECO:0000313|Proteomes:UP000249239};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PZX15143.1}.
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DR   EMBL; QKZK01000017; PZX15143.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2W7N604; -.
DR   OrthoDB; 9124519at2; -.
DR   Proteomes; UP000249239; Unassembled WGS sequence.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00082; HisKA; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 3.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR   PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   Pfam; PF00989; PAS; 2.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SMART; SM00091; PAS; 3.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50112; PAS; 2.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000249239}.
FT   DOMAIN          204..258
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          333..379
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          586..801
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   819 AA;  93552 MW;  17B6913A24AD675F CRC64;
     MKKRRFYSSI YDRPDTSITK DESLTFSERD EDLSDFSKWV ALMDEIDVDA LGCSSFSVED
     FVQADWFQRF HEPMCLLGAG GKVLCHNVAF GTHVLSYRRG EDVLVIGQLL TPEKADWFEG
     LFVTGAYNHS DHLHHWVTYL SPSGELMRGA IEAYPIELES MWVLILHVSC EHDSDDYQPV
     CLTDKYKMAF EISPDVICIT RLSDGFFVEV NDNFLKFSGY EMHEVIGKTS LDLNFWAEPQ
     QRDILLQKLI LEGSIDNVEI QFRLKDGSIA EAMVSMRTIS VNHQAHLFLF ARDIRYRKEL
     EFKYRLLFEN LSSGFALLES KFSSQREMNV FVFVDVNPAF ETILGFTSDQ IVGREINDVI
     PHLDVEMHDA LLEVANDGQF KRCVDERFIE GKKFRIMVFC PKKGFIAILF EDITEMMRQQ
     DELHERDEQL RQMFEHTHSV LMLLNRDGEL VRLNRAGFEL AAHLNSDYSG LRPGNLMNCV
     GTINNPRGCG LGPVCKTCRL RKMARETYVS GKSFIREEIW VSQMNQGAVR RLYLLVSISR
     LILKSGTHLL ISIDDITRRK IMEDDLVSAK QRAEESDRLK TAFFSNLSHE IRTPLNGIIG
     FSNLLKKKDI SPSDLSLYTH YINENSNRLL MIMNNVIELA QLNSHLMKIV NSEFDLEKAV
     VETLRIGKTM NPEKQLNVRY KIVGDKQVIG YPTVFTSALK QLVLNSYKFT LFGSIGVKCT
     TSAGRLCCIV ADTGIGIEAS FQDLIFEPFR QQEDGMTRNY GGIGLGLAIV KEYMKLVDGS
     ITLKSIPGRG SVFRIEMPVM SSEQFDVSRS KVDFSVKKN
//