ID A0A2X0I9M3_9ACTN Unreviewed; 332 AA.
AC A0A2X0I9M3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:RAG80343.1};
GN ORFNames=DN069_38675 {ECO:0000313|EMBL:RAG80343.1};
OS Streptacidiphilus pinicola.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptacidiphilus.
OX NCBI_TaxID=2219663 {ECO:0000313|EMBL:RAG80343.1, ECO:0000313|Proteomes:UP000248889};
RN [1] {ECO:0000313|EMBL:RAG80343.1, ECO:0000313|Proteomes:UP000248889}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMS16-CNU450 {ECO:0000313|EMBL:RAG80343.1,
RC ECO:0000313|Proteomes:UP000248889};
RA Roh S.G., Park S., Kim M.-K., Yun B.-R., Park J., Kim M.J., Kim Y.S.,
RA Kim S.B.;
RT "Streptacidiphilus pinicola sp. nov., isolated from pine grove soil.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAG80343.1}.
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DR EMBL; QKYN01000255; RAG80343.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2X0I9M3; -.
DR OrthoDB; 582216at2; -.
DR Proteomes; UP000248889; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR031725; ASMT_dimerisation.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF16864; Dimerisation2; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:RAG80343.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000248889};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:RAG80343.1}.
FT DOMAIN 11..90
FT /note="Acetylserotonin O-methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF16864"
FT DOMAIN 147..314
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
SQ SEQUENCE 332 AA; 35469 MW; C4F4003C14D73295 CRC64;
MTGTQPSPSR ILEIASGYWA TGLLAVATQN SLFTLIHDGR RTPAELADKT GLALRGVQTL
LDGLVGLGLL HTQDGVYRNT PETDLYLVEG QLTDISGLAQ LKLAEMDNLV GRLEVFRAGG
PLNNPVAEVA DNPHWENVVT AIAGLSVAAA QTAASVLSLA DWKNLSILDV GGGSGVFSSV
WLQLNPTAQA TQLDWEPINA IARRLLSNHD LTGRFSCLDG DFHTTELEAA AYDVALYSHI
AHQEGPEDNT AVFAKLRDAL KPGGALIVCD YIVDDDRSGP PFSLLFASEM LLKTNHGGTW
RRADYAAWLI QAGFTDVTFH ATGTPATLAI AR
//
