ID A0A2X0KK04_9BASI Unreviewed; 370 AA.
AC A0A2X0KK04;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=poly(A)-specific ribonuclease {ECO:0000256|ARBA:ARBA00012161};
DE EC=3.1.13.4 {ECO:0000256|ARBA:ARBA00012161};
GN ORFNames=BZ3500_MVSOF-1268-A1-R1_CHR5-3G08302
GN {ECO:0000313|EMBL:SCZ92048.1};
OS Microbotryum saponariae.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX NCBI_TaxID=289078 {ECO:0000313|EMBL:SCZ92048.1, ECO:0000313|Proteomes:UP000249723};
RN [1] {ECO:0000313|Proteomes:UP000249723}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jeantristanb JTB J.-T., Ricardo R.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage of poly(A) to 5'-AMP.; EC=3.1.13.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001663};
CC -!- SIMILARITY: Belongs to the CAF1 family.
CC {ECO:0000256|ARBA:ARBA00008372}.
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DR EMBL; FMWP01000017; SCZ92048.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2X0KK04; -.
DR STRING; 289078.A0A2X0KK04; -.
DR Proteomes; UP000249723; Unassembled WGS sequence.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:UniProtKB-EC.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProt.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR039637; CNOT7/CNOT8/Pop2.
DR InterPro; IPR006941; RNase_CAF1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10797; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT; 1.
DR PANTHER; PTHR10797:SF0; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7; 1.
DR Pfam; PF04857; CAF1; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000249723};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 370 AA; 41156 MW; BFFB2B9E8C01B01F CRC64;
MQQLHNMGRN GPPPPPSHGP PPLSNQHQQH QQQPQLQQPP QQQAGPAAGV VVRPGEEPRI
REVWANNLEE EMAHIRASIE KYPYVAMDTE FPGVVARPIG SFRGSSDYHY QTLRCNVDLL
RIIQLGLTLA EQNGELAPGV CTWQFNFKFN INDDMFAPES IELLVKSGIN FKRNEEYGID
VEHFGELLIS SGLVLLEDVQ WVSFHSGYDF GYLLKIVSCA PLPPTEAEFF DLLRIWFPCI
WDIKYLMKSC KSLKGGLQEV ADDLQVPRVG PQHQAGSDSL LTAATFFKMR GKFFDDALDN
KFMGVLYGLN SSSTERNPAH PREHNGAVHY PHPAQTQPPA SVPPQNVTPL AAATSAAIAI
MSPSRNNTGR
//
