ID   A0A2X0KLS5_9BASI        Unreviewed;       357 AA.
AC   A0A2X0KLS5;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=BZ3500_MvSof-1268-A1-R1_Chr12-3g04049 protein {ECO:0000313|EMBL:SCZ94692.1};
GN   ORFNames=BZ3500_MVSOF-1268-A1-R1_CHR12-3G04049
GN   {ECO:0000313|EMBL:SCZ94692.1};
OS   Microbotryum saponariae.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC   Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX   NCBI_TaxID=289078 {ECO:0000313|EMBL:SCZ94692.1, ECO:0000313|Proteomes:UP000249723};
RN   [1] {ECO:0000313|Proteomes:UP000249723}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Jeantristanb JTB J.-T., Ricardo R.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. Dihydroflavonol-4-reductase subfamily.
CC       {ECO:0000256|ARBA:ARBA00023445}.
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DR   EMBL; FMWP01000053; SCZ94692.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2X0KLS5; -.
DR   STRING; 289078.A0A2X0KLS5; -.
DR   Proteomes; UP000249723; Unassembled WGS sequence.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   CDD; cd05227; AR_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR10366:SF564; 3BETA_HSD DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000249723}.
FT   DOMAIN          15..281
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
SQ   SEQUENCE   357 AA;  39588 MW;  B1D3412A5B94B261 CRC64;
     MIAVDLARTR ASVLLTGASG FLAAHVGQQL LQRGFRVRGT VRSQAKGEYL KKLYEKDGKA
     DRFDFVIVED VEQEGAFDEA VKGVDAVAYT ASPFHFNVTD PQKDLINPAV QGTLNLVRSA
     LLEPKIKRVV ITSSFAAVTN PYDPVYTFTE EDWNEFSPKE LEKKGKDCDP FHSYRASKTL
     AEKAAWDFLK ENTKDGKAPF DIATINPPLI FGPVIHEIHS AKSLNTSVGV FYSYLLGDKT
     SEDATKPAGL LVDVRDVALA HVLALEKEEA GNKRFLVSKK EFVYQDILDL LEGSEQGKKL
     LSEFPKATKS GKGDVKGVKQ NLIDTTRMET VLGLKARSVE ETVLDMTRSL AERQKEW
//