ID   A0A2X0MQM0_9BASI        Unreviewed;      1220 AA.
AC   A0A2X0MQM0;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE            EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
GN   ORFNames=BZ3500_MVSOF-1268-A1-R1_CHR1-3G01634
GN   {ECO:0000313|EMBL:SCZ89879.1};
OS   Microbotryum saponariae.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC   Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX   NCBI_TaxID=289078 {ECO:0000313|EMBL:SCZ89879.1, ECO:0000313|Proteomes:UP000249723};
RN   [1] {ECO:0000313|Proteomes:UP000249723}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Jeantristanb JTB J.-T., Ricardo R.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMWP01000014; SCZ89879.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2X0MQM0; -.
DR   STRING; 289078.A0A2X0MQM0; -.
DR   Proteomes; UP000249723; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 1.10.340.70; -; 1.
DR   Gene3D; 3.10.20.370; -; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR041588; Integrase_H2C2.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041373; RT_RNaseH.
DR   PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR   Pfam; PF13650; Asp_protease_2; 1.
DR   Pfam; PF17921; Integrase_H2C2; 1.
DR   Pfam; PF17917; RT_RNaseH; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000249723};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW   Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT   DOMAIN          311..496
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   DOMAIN          853..1012
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
SQ   SEQUENCE   1220 AA;  137232 MW;  07B46A40681BE5D3 CRC64;
     MEALREYFMR LEYYNRRVAQ SSNCPRYAPA PGAPATSSTP LSTAPAARTR PGMVAAIQTF
     QETGDSTAFA GLNSDSEDDD YSCAPRSFPP LPVSLRGAHG TLTASALVDS GSPQTFLSED
     FVQRLGLEKR ALEQHTKYTL AMQNQVPTVF TCTHFVRVPV ELADGRWAAG PTYAEVAPLG
     RDLELILGGN FIYTHKIDLG HFPHPHFTCK NNPEEPIDLL ELSSQPRGTS PVAAIAPVNE
     DEQLRLAALD QRLRAVYADR FPDDIPPVAT YQSPVRHHIE LDNPRTVINL RGYPVAKRHR
     QAWYLLLQKH LASGRLRPSR SPYASPAFII PKKGSDVDPT IAPRWVNDYR HLNRHTIKDR
     TPLPLADDIL STCSKAQFWA KIDMTNSFFQ TKMAEEDIAK TAVSTPWGLY EWTVMPMGLC
     KAPATHQRRV NDALHGLLGT ICFVYLDDIT IFADTLEEHE ARVCQVLDAL RRAELYCSPS
     KTNLATSECE FLGHIINRSG VHADPKKIKR IHDWHLPATV TELKGFLGLV QYLRRFIPGL
     AEHTAALTPL TIKGLTSIDN LWTTPTVCHF EAMKSIVVSL DCLRPPDHSA DAMPFWVMTD
     ASLQGIGGVL LQGSHWKTAH PIAYWSRQYI PAERNYPTHE QELLAIVEAL KEWRIDLLGG
     HFHILTDHST LEHFQTQRTV ISRRQARWLD TLAEFDYDLQ YIPGRENIVA DAMSRYSFPE
     PLPVIVANIS QVSLSDVVKQ QIVDAYKTDA FCQQALNNIA SVASEFKIID ALLYLRGRLV
     IPLLAPLRES ILHDAHDALG HLGDVKTYQT VIQTYFWPNM SRHVKQYVQQ CDSCQRTKAR
     TTRVAGKLHS LPVPVRPMTD IAVDFVGPLP TNKGFDRVLT ITDRLSGYVR LIPAREADTA
     ADVANRFHEG WHRFFGLPQR IVSDRDKLFT SKFWSALHKR LNIKLQLSSA FHPETDGRSE
     KTNKTAFQIL RSLVNREQSN WVECLTACEY AINSSVNVST GKTPFELVLG YTPTLAPLAP
     IEGDEELPSV EELLALRFQS CEEARDQLAV SKVRQAAQAN KDRADEPSWA VGDLVLLDSS
     DRRKRLHTRK RRAAKLMDRF DGPYRIDDSA VPFFHTGKLK AYRSNDSELF PSREPARPGP
     VDVGGEPELN IWSLGFHGRR IAIHGSLPRH WRTRRHWSVG NIGTRNESVF SEGSFVSRRG
     ECKARPYDGP QALEIELARA
//