ID A0A2X0N0F9_9BASI Unreviewed; 2034 AA.
AC A0A2X0N0F9;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN Name=BQ5605_C006g04180 {ECO:0000313|EMBL:SGY56844.1};
GN ORFNames=BQ5605_C006G04180 {ECO:0000313|EMBL:SGY56844.1};
OS Microbotryum silenes-dioicae.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX NCBI_TaxID=796604 {ECO:0000313|EMBL:SGY56844.1, ECO:0000313|Proteomes:UP000249464};
RN [1] {ECO:0000313|EMBL:SGY56844.1, ECO:0000313|Proteomes:UP000249464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
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DR EMBL; FQNC01000044; SGY56844.1; -; Genomic_DNA.
DR Proteomes; UP000249464; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 2.40.50.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR025476; Helitron_helicase-like.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR45786:SF82; ATP-DEPENDENT DNA HELICASE; 1.
DR PANTHER; PTHR45786; DNA BINDING PROTEIN-LIKE; 1.
DR Pfam; PF00385; Chromo; 1.
DR Pfam; PF14214; Helitron_like_N; 1.
DR Pfam; PF05970; PIF1; 1.
DR Pfam; PF00665; rve; 1.
DR SMART; SM00298; CHROMO; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50013; CHROMO_2; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW Reference proteome {ECO:0000313|Proteomes:UP000249464};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT DOMAIN 1140..1299
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT DOMAIN 1441..1502
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT REGION 1..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 837..871
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 56..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..98
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..476
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2034 AA; 230124 MW; 08A6D25EACFA9A05 CRC64;
MALRPLPEDQ LHPMDPPPMN AAISRRSQGQ QRRRQRESLQ RERSVPVPHS VPPDPVFAKS
TNQSTSRRTE QNNCIEQSPP PEPTPDVHSV PQRQPHSPEP PGARSVRARL HPPATQSPMA
LRPLPEGPYP RHDLGPMDLL CPKCSAFHWD FERLGGRQNS EFRSCCDDGK VELPKIRKPP
NTLLELLTGD GQGMLDIMPL FFGAVHLTKT PCTVCTVEKL FRERILAFNE NLAMASFGTS
QDYGIIGAGG PPSFYLSGNV YHRMGTLAPA RSSNPVFAQI LFVAPSERID ARIRFNGPSS
DDEQQLVIAY RQILPRLDEM MLQENRRAQQ FLMAREFINR EDAHAYQLRL LAPRNRDPRR
YNLPTQDEVA VILPGDETEH RSSSWEIVVR LRSPPYGDTT SGLQILPDKH PAVMSLTYRL
LLPFGEDWYQ DNIPFSQNAS TSLADRRTRD ADGVLQRTHG SGSTTADNPQ TGRGGSKHVT
PLQFNAYYFH IWPETVSFPT LFLGGQLFQK FVADAGALTE QDRLQWITTN QKTLRAEEYS
SLQASLAEGI DPSEIGKRVI LPSSYPSSPR NMVQLYKDAM AIVRAFGAPD LFITMTCNPA
WPEIINALLP GQTASNRPDI VARVFQGKLT ACLHDIYGDH GRPGVFGRVV AHVHVIEFQK
RGLPHAHILL ILHPDEKPKT NEDFDRIVTA EIPDQEKFPT LFETITNSML HRRCDLPGQH
TCHDKYGKCS KGFPKQFQDR TTSEDGGYPH YRRRNLHQFI NYLYDLAPQS LPLASTCFHE
FLSLSLGFPS TINRASYSYK NNYINPTSRP VILAIACCLR LSNLNPDSRS RFPIDLVDLT
QASLDSLIDQ LRTLQARNQA LEAECRSHLS DKENYQITVT ALANQQQTLS DFAKAVVDQQ
KESIDVIKSG LANLNVTAPA NTTITPVKSQ LAKPDKYDGK EKVKFKTFIT QIKFCIFGNP
SSFPTDESKI AFIISHLTGD AFQHFEHAIN AKDDSKPEWL TNYQKFLDQA ELVLGDPDYR
NNLTRQLMSL VQSGPASVYA SKFTQISSQL DWNQAALIAH FHKGLKLGLQ AQLALHDDPQ
DLQSLIELAI KVDNKLHLAR HRTNASTQFR QTNWQYSHSV NSPLRTSPVS QLQANPSTAN
TSKPWSSLSM DHIVDLPPSS GFDCVLVVVD RLTKEAHFIP THKTDSSRDL ARTFLTHVFK
LHGLPTDIVS DRGATFTSNW WSEFLAMLKI KPNLSTAFHP ESDGQTERTN QTLEHYHRHF
CDYLQTNWSE LLPLAEFAYN NSFHLSIGAS PFYVTRGYHP RLEVSLRDSF VTDVPKYLQH
LRSVQETARK QILQAQETQA RFANLKRKPS PPFKIGDQVL LNRKNIQTSR PSSKLDSHKL
GPFRIQRIIS PAAFKLELPA SMKIHPVFHV SLLEPYQANS LASRCSNPPP PPEIINGEEE
YQVEQILDSR NNRRSRRLEY FVDWTGYGPQ DRQWVSAADF DDDDSLVIEF HTRHPHKPGF
ERIQGLNGAR ASSYLYDLAP RSLPLASTCF HEFLSLSLGF PSTINRASYS YKNNYINPAC
RPFPGTEWEE IYTDVNVVPT NPWLASKYDC HINVEIANGV AAVKYHYKYV YKGHDRTLFT
VEAGAPRNEV KDFLDARYVC APEAMHRLFQ YQMHGHKPAV TRLALHLPNE QQVRFDPEDG
PLTTAAPPET TLTAFVKLCA TVPPVPKAQN VLYLDVPRSF RWDLNKRAWQ ERKKNTPAIG
RMYFCGPEAG ERYYLRLLLL NVPSPTSFAQ LRTFNGTEFK TFREACIERG LLQDNTEANR
CLTEAAVFHS GHQLRHLFAM LLTADGGVSN AAELWETHHN SLSDDAEYHL LMRRGQSFIT
PEHISSWALL QLEQILQRLG TSLCDHGLPL PTATFKNELE LSRLMMEERS TPEEIERMNR
EWMKNLEAFT VEQRHAFDTI CDSVFNAQGK TFFINAPGGT GKTFLETTIL SRIRSENKYA
LAVASSGIAA LLLPKGRTAH SRFKIPIDIF DDSTCNVHKQ GQLAELFRAC ELIV
//
