ID A0A2X0NE55_9BASI Unreviewed; 418 AA.
AC A0A2X0NE55;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=acetyl-CoA C-acyltransferase {ECO:0000256|ARBA:ARBA00024073};
DE EC=2.3.1.16 {ECO:0000256|ARBA:ARBA00024073};
GN Name=BQ5605_C023g09747 {ECO:0000313|EMBL:SGZ24796.1};
GN ORFNames=BQ5605_C023G09747 {ECO:0000313|EMBL:SGZ24796.1};
OS Microbotryum silenes-dioicae.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX NCBI_TaxID=796604 {ECO:0000313|EMBL:SGZ24796.1, ECO:0000313|Proteomes:UP000249464};
RN [1] {ECO:0000313|EMBL:SGZ24796.1, ECO:0000313|Proteomes:UP000249464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; FQNC01000085; SGZ24796.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2X0NE55; -.
DR STRING; 796604.A0A2X0NE55; -.
DR Proteomes; UP000249464; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003988; F:acetyl-CoA C-acyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43853; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR PANTHER; PTHR43853:SF9; ACETYL-COA C-ACETYLTRANSFERASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000249464};
KW Transferase {ECO:0000256|RuleBase:RU003557}.
FT DOMAIN 22..287
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 295..416
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 111
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 374
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 404
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 418 AA; 44335 MW; 44F402D589036E73 CRC64;
MVQATVVRRS LSNILKKNAH DVVIVTSLRT PIAKFRGAYK DMYPEELLSH VLKSTRKKLE
AQGVDVQSGL VEDIHVGTVL MELGGAKSGR LASLDAGFPI VSGFKAVNRQ CASSLQSVTD
IAQSIQSGMI DMGVAAGVEH MTRDYGTRAI PVNISRFIKK SESQDAQDCL MPMGMTSENV
AAEHGYSRQQ QDEFACASHA KAKAAQDAGY LAEEIVPIKV RSVTPAEGDK PESTEIKTIS
KDEGIRPQTT MESLAKLKPA FKAEGTGTAG NSSQISDGAS ALTLVRRDVA EKLGLKPLAK
WVGSAVVGVP PRIMGVGPAY AVPKLFERFG ISKDDVDIFE LNEAFASQSL MVIETLGLDI
KKVNPKGGAI ALGHPLGATG GRLLSSLIYE LKRTDKKVGV ATLCMGTGAG KATLIAAE
//
