ID A0A2X0S254_WHEAT Unreviewed; 656 AA.
AC A0A2X0S254;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:SPT16656.1};
GN ORFNames=CAMPLR22A2D_LOCUS1256 {ECO:0000313|EMBL:SPT16656.1},
GN CFC21_028435 {ECO:0000313|EMBL:KAF7014442.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2D02G142000.2};
RN [1] {ECO:0000313|EMBL:KAF7014442.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7014442.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2D02G142000.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2D02G142000.2};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EMBL:SPT16656.1, ECO:0000313|Proteomes:UP000280104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Thind KAUR A.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EnsemblPlants:TraesCS2D02G142000.2}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [5] {ECO:0000313|EMBL:KAF7014442.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7014442.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022216; KAF7014442.1; -; Genomic_DNA.
DR EMBL; LS480641; SPT16656.1; -; Genomic_DNA.
DR SMR; A0A2X0S254; -.
DR STRING; 4565.A0A2X0S254; -.
DR EnsemblPlants; TraesCS2D02G142000.2; TraesCS2D02G142000.2; TraesCS2D02G142000.
DR Gramene; TraesCS2D02G142000.2; TraesCS2D02G142000.2; TraesCS2D02G142000.
DR Gramene; TraesCS2D03G0298300.2; TraesCS2D03G0298300.2.CDS; TraesCS2D03G0298300.
DR OMA; THPKENY; -.
DR OrthoDB; 350891at2759; -.
DR Proteomes; UP000019116; Chromosome 2D.
DR Proteomes; UP000280104; Chromosome ii.
DR Proteomes; UP000815260; Chromosome 2D.
DR ExpressionAtlas; A0A2X0S254; baseline.
DR GO; GO:0070531; C:BRCA1-A complex; IBA:GO_Central.
DR GO; GO:0031436; C:BRCA1-BARD1 complex; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IBA:GO_Central.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; IBA:GO_Central.
DR GO; GO:0035067; P:negative regulation of histone acetylation; IBA:GO_Central.
DR GO; GO:0035066; P:positive regulation of histone acetylation; IBA:GO_Central.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031099; BRCA1-associated.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13763; BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; 1.
DR PANTHER; PTHR13763:SF6; PHD-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR SMART; SM00292; BRCT; 2.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 2.
DR PROSITE; PS51805; EPHD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 137..259
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 420..492
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 539..579
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 82..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 656 AA; 71130 MW; 41013EE1E434E425 CRC64;
MGMRGRPRRG SRGITSSPPP GFGPAAAAAR PSSARSAGTN SAARTGMLFN VEIQPGYADP
ESLRHVWNRS ASPMKGRKRK FGVDATKGES PGINASNTGE HLRSCRKGKG PGKRARLVDK
EGATGLGRVQ TPTGLYEDEC AFCQSFRTSE PVHGPLVLYH NGRIVSSDEA DATNAIYVHF
KCMVWAPKVK SNDDGTFENV ESEIERGSRW DCSRCNLRGA ALGCYRAGCP NTYHVPCAFM
IPECRWDVEN LHVWCPMHAP PDEMSSPTIE TGILSPDPQN QSPANEISAD CQMEDNQINP
LLGNEMSSPI IGSDIPSTVL QNSCPAKEIS VDCQMEDKQF NPLVTSNSPL PGLVPGSSQY
LIKEGISALH RGEDLQVDQL NTSSSSSPQG QCTDKEGIST NYRAEDKLAN QSSTPLDQWV
LLGIALSASE KDSLKEFASL TSSTLAQEWD KTVTHVIVGR NAGSRCGRSY EVQMAILSGK
WVVAAGWVVD CLVERISGPK PCLAKLIPSP EISYEVKFYD GARTSIDGPA KGRAGAAEGA
RKLLSGLHFC FSAYMHPEDR EDIQNLIAAG GGQVLEGISP DGLRENLKRN PAEVYFIYHG
GPPRTPTSDF DLEVQECNKY VGSGARMIRH LQLFDAILCY DVLFLKPTGV FTKICK
//
