ID A0A2X2EL75_RAOPL Unreviewed; 340 AA.
AC A0A2X2EL75;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=LacI family DNA-binding transcriptional regulator {ECO:0000313|EMBL:RWT19704.1};
DE SubName: Full=Purine nucleotide synthesis repressor {ECO:0000313|EMBL:VFS55367.1};
GN Name=purR_1 {ECO:0000313|EMBL:VFS55367.1};
GN ORFNames=DN603_20655 {ECO:0000313|EMBL:RWT19704.1}, NCTC12998_00068
GN {ECO:0000313|EMBL:VFS55367.1};
OS Raoultella planticola (Klebsiella planticola).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Raoultella.
OX NCBI_TaxID=575 {ECO:0000313|EMBL:RWT19704.1, ECO:0000313|Proteomes:UP000288843};
RN [1] {ECO:0000313|EMBL:RWT19704.1, ECO:0000313|Proteomes:UP000288843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GEO_47_Down_B {ECO:0000313|EMBL:RWT19704.1,
RC ECO:0000313|Proteomes:UP000288843};
RA Mathys D.A., Mollenkopf D.F., Feicht S.M., Adams R.J., Albers A.L.,
RA Stuever D.M., Daniels J.B., Wittum T.E.;
RT "Carbapenemase-producing Enterobacteriaceae present in wastewater treatment
RT plant effluent and nearby surface waters in the US.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:VFS55367.1, ECO:0000313|Proteomes:UP000345637}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12998 {ECO:0000313|EMBL:VFS55367.1,
RC ECO:0000313|Proteomes:UP000345637};
RG Pathogen Informatics;
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; QKOX01000024; RWT19704.1; -; Genomic_DNA.
DR EMBL; CAADJE010000001; VFS55367.1; -; Genomic_DNA.
DR RefSeq; WP_032687612.1; NZ_VLNM01000003.1.
DR AlphaFoldDB; A0A2X2EL75; -.
DR Proteomes; UP000288843; Unassembled WGS sequence.
DR Proteomes; UP000345637; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR001761; Peripla_BP/Lac1_sug-bd_dom.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF109; TRANSCRIPTIONAL REGULATOR LACI_GALR-LIKE SENSOR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF00532; Peripla_BP_1; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:RWT19704.1};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..64
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT DOMAIN 12..54
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 340 AA; 37831 MW; 1E8396460C72E20C CRC64;
MAQEMSIKRV LLSDVAKLAG LSKATLSRYM NNSIVLPQET IDRIETAIRE LDYRGNSLAR
RLSKGGSETL GLVLPDITNP FFAELADAAE EAASAHGYSL VLCITRNNPE KECQFIRWLD
TCQVDGLLFT TNRPDNGLLR KEVQRHERIV LLDEDIPGSK VPKVFADNVQ GGRIATEKLI
AAGHRHIAFV GGPDKLMSVR ERYQGFCTAM EQAGLSWPAE WVMYGDYQRE FGQQALQYLF
SQPVRPTAVF AASDYLVLGL LDGLRASGLQ APEALSLVGF DDASYADFTQ PRISTIRQPA
RELGRTAVNI MMRLLNDDKD IPAETRLPVE WIGRDSIKIC
//
