ID A0A2X3E576_KLUCR Unreviewed; 359 AA.
AC A0A2X3E576;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=EIIBCA-Man {ECO:0000313|EMBL:VFS68264.1};
DE SubName: Full=PTS fructose transporter subunit EIIC {ECO:0000313|EMBL:HAT1572693.1};
GN Name=manP_7 {ECO:0000313|EMBL:VFS68264.1};
GN ORFNames=I8Y10_004101 {ECO:0000313|EMBL:HAT1572693.1}, NCTC12993_03947
GN {ECO:0000313|EMBL:VFS68264.1};
OS Kluyvera cryocrescens (Kluyvera citrophila).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Kluyvera.
OX NCBI_TaxID=580 {ECO:0000313|EMBL:HAT1572693.1};
RN [1] {ECO:0000313|EMBL:HAT1572693.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=88CZ1 {ECO:0000313|EMBL:HAT1572693.1};
RX PubMed=30286803;
RA Souvorov A., Agarwala R., Lipman D.J.;
RT "SKESA: strategic k-mer extension for scrupulous assemblies.";
RL Genome Biol. 19:153-153(2018).
RN [2] {ECO:0000313|EMBL:VFS68264.1, ECO:0000313|Proteomes:UP000401081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12993 {ECO:0000313|EMBL:VFS68264.1,
RC ECO:0000313|Proteomes:UP000401081};
RG Pathogen Informatics;
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:HAT1572693.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=88CZ1 {ECO:0000313|EMBL:HAT1572693.1};
RG NCBI Pathogen Detection Project;
RL Submitted (NOV-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DACSDP010000021; HAT1572693.1; -; Genomic_DNA.
DR EMBL; CAADJD010000020; VFS68264.1; -; Genomic_DNA.
DR RefSeq; WP_061284430.1; NZ_VKGH01000012.1.
DR AlphaFoldDB; A0A2X3E576; -.
DR OrthoDB; 9782569at2; -.
DR Proteomes; UP000401081; Unassembled WGS sequence.
DR Proteomes; UP000863970; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005351; F:carbohydrate:proton symporter activity; IEA:InterPro.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013014; PTS_EIIC_2.
DR InterPro; IPR006327; PTS_IIC_fruc.
DR NCBIfam; TIGR01427; PTS_IIC_fructo; 1.
DR PANTHER; PTHR30505; FRUCTOSE-LIKE PERMEASE; 1.
DR PANTHER; PTHR30505:SF34; FRUCTOSE-LIKE PERMEASE IIC COMPONENT 2; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR PROSITE; PS51104; PTS_EIIC_TYPE_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000401081};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 22..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..344
FT /note="PTS EIIC type-2"
FT /evidence="ECO:0000259|PROSITE:PS51104"
SQ SEQUENCE 359 AA; 37436 MW; AE287ECEBD119BEF CRC64;
MKELVQILRN TRQHLMTGVS HMIPFVVAGG ILLAVSVMLY GKGAVPDVAT DPNLKKLFDI
GVAGLTLMVP FLAAYIGYSI AERSALAPCA IGAWVGNSFG AGFFGALIAG IIGGIVVYYL
KKIPVHKVLR SVMPIFVIPI IGTLITAGIM MWGLGEPVGM LTNSLTHWLQ GMQAGSIVVL
AVIMGLMLAF DMGGPVNKVA YAFMLICVSQ GVYTVVAIAA VGICVPPLGL GLATLINRKN
FNNEEREAGK AALVMGCVGV TEGAIPFAAA DPLRVIPSIM LGSVCGAVTA ALMGAQCYAG
WGGLIVLPVV EGKLGYLLAI VVGAVVTAVS VNLLKSLARK NKKVAVEKED DLDLDFEIN
//
