ID A0A2X4SYU0_SALER Unreviewed; 241 AA.
AC A0A2X4SYU0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Lipopolysaccharide export system ATP-binding protein LptB {ECO:0000256|ARBA:ARBA00017803};
GN Name=lptB {ECO:0000313|EMBL:SQI20081.1};
GN ORFNames=AHX45_09255 {ECO:0000313|EMBL:EDH0570389.1}, FLP03_11285
GN {ECO:0000313|EMBL:ECF4922773.1}, GBZ58_12215
GN {ECO:0000313|EMBL:HAB4461346.1}, NCTC10047_00675
GN {ECO:0000313|EMBL:VEA74876.1}, NCTC7295_00588
GN {ECO:0000313|EMBL:SUG13035.1}, NCTC7304_00663
GN {ECO:0000313|EMBL:SUG31293.1}, NCTC7307_00624
GN {ECO:0000313|EMBL:SQI20081.1}, T044_13330
GN {ECO:0000313|EMBL:EBP3763545.1};
OS Salmonella enterica subsp. arizonae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=59203 {ECO:0000313|EMBL:SQI20081.1, ECO:0000313|Proteomes:UP000248731};
RN [1] {ECO:0000313|EMBL:HAB4461346.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Salmonella enterica {ECO:0000313|EMBL:HAB4461346.1};
RX PubMed=30286803;
RA Souvorov A., Agarwala R., Lipman D.J.;
RT "SKESA: strategic k-mer extension for scrupulous assemblies.";
RL Genome Biol. 19:153-153(2018).
RN [2] {ECO:0000313|Proteomes:UP000248731, ECO:0000313|Proteomes:UP000254124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC7295 {ECO:0000313|EMBL:SUG13035.1,
RC ECO:0000313|Proteomes:UP000254124}, NCTC7304
RC {ECO:0000313|EMBL:SUG31293.1, ECO:0000313|Proteomes:UP000254762}, and
RC NCTC7307 {ECO:0000313|EMBL:SQI20081.1,
RC ECO:0000313|Proteomes:UP000248731};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EBP3763545.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FAR0179 {ECO:0000313|EMBL:EBP3763545.1}, FDA00001204
RC {ECO:0000313|EMBL:EDH0570389.1}, and FDA00014297
RC {ECO:0000313|EMBL:ECF4922773.1};
RG GenomeTrakr network: Whole genome sequencing for foodborne pathogen traceback;
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:VEA74876.1, ECO:0000313|Proteomes:UP000275676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10047 {ECO:0000313|EMBL:VEA74876.1,
RC ECO:0000313|Proteomes:UP000275676};
RG Pathogen Informatics;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:HAB4461346.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Salmonella enterica {ECO:0000313|EMBL:HAB4461346.1};
RG NCBI Pathogen Detection Project;
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the ABC transporter complex LptBFG involved in the
CC translocation of lipopolysaccharide (LPS) from the inner membrane to
CC the outer membrane. Probably responsible for energy coupling to the
CC transport system. {ECO:0000256|ARBA:ARBA00024818}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. The LptBFG transporter is composed of two ATP-binding proteins
CC (LptB) and two transmembrane proteins (LptF and LptG).
CC {ECO:0000256|ARBA:ARBA00026081}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004515}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004515}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004515}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Outer membrane
CC lipopolysaccharide export (TC 1.B.42) family.
CC {ECO:0000256|ARBA:ARBA00010865}.
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DR EMBL; AAGLNU010000010; EBP3763545.1; -; Genomic_DNA.
DR EMBL; AAILJL010000007; ECF4922773.1; -; Genomic_DNA.
DR EMBL; AAMGFJ010000008; EDH0570389.1; -; Genomic_DNA.
DR EMBL; DAAGTC010000006; HAB4461346.1; -; Genomic_DNA.
DR EMBL; LS483466; SQI20081.1; -; Genomic_DNA.
DR EMBL; UGWZ01000001; SUG13035.1; -; Genomic_DNA.
DR EMBL; UGXD01000002; SUG31293.1; -; Genomic_DNA.
DR EMBL; LR134156; VEA74876.1; -; Genomic_DNA.
DR RefSeq; WP_000224104.1; NZ_JANDEZ010000001.1.
DR AlphaFoldDB; A0A2X4SYU0; -.
DR SMR; A0A2X4SYU0; -.
DR GeneID; 66757658; -.
DR OMA; VTSWCAQ; -.
DR Proteomes; UP000248731; Chromosome 1.
DR Proteomes; UP000254124; Unassembled WGS sequence.
DR Proteomes; UP000254762; Unassembled WGS sequence.
DR Proteomes; UP000275676; Chromosome 1.
DR Proteomes; UP000839641; Unassembled WGS sequence.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd03218; ABC_YhbG; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR032823; BCA_ABC_TP_C.
DR InterPro; IPR030921; LPS_export_LptB.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR04406; LPS_export_lptB; 1.
DR PANTHER; PTHR45772; CONSERVED COMPONENT OF ABC TRANSPORTER FOR NATURAL AMINO ACIDS-RELATED; 1.
DR PANTHER; PTHR45772:SF10; LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF12399; BCA_ABC_TP_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:SQI20081.1};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hydrolase {ECO:0000313|EMBL:SQI20081.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000248731}.
FT DOMAIN 4..237
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 241 AA; 26797 MW; 86C7B96D0B183AD8 CRC64;
MATLTAKNLA KAYKGRRVVE DVSLTVNSGE IVGLLGPNGA GKTTTFYMVV GIVPRDAGNI
IIDDEDISLL PLHARARRGI GYLPQEASIF RRLSVFDNLM AVLQIRDDLT AEQREDRANE
LMEEFHIEHL RDSMGQALSG GERRRVEIAR ALAANPKFIL LDEPFAGVDP ISVIDIKRII
EHLRDSGLGV LITDHNVRET LAVCERAYIV SQGHLIAHGT PTEILQDEHV KRVYLGEDFR
L
//
