ID A0A2X4VZR6_SALER Unreviewed; 185 AA.
AC A0A2X4VZR6;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=C-terminal Zn-finger domain of DNA topoisomerase I-like protein {ECO:0000313|EMBL:SQI19955.1};
DE EC=5.99.1.2 {ECO:0000313|EMBL:SQI19955.1};
DE SubName: Full=Topoisomerase DNA-binding C4 zinc finger domain-containing protein {ECO:0000313|EMBL:QXW48725.1};
GN Name=topA_1 {ECO:0000313|EMBL:SQI19955.1};
GN Synonyms=topA_5 {ECO:0000313|EMBL:SUG50646.1};
GN ORFNames=AHX45_20895 {ECO:0000313|EMBL:EDH0572506.1}, DSQ81_22385
GN {ECO:0000313|EMBL:ECI4938350.1}, F4V61_21520
GN {ECO:0000313|EMBL:KAA8661746.1}, GBZ58_05555
GN {ECO:0000313|EMBL:HAB4460120.1}, KX325_17150
GN {ECO:0000313|EMBL:QXW48725.1}, NCTC7295_00491
GN {ECO:0000313|EMBL:SUG12947.1}, NCTC7303_02939
GN {ECO:0000313|EMBL:SUG50646.1}, NCTC7304_00565
GN {ECO:0000313|EMBL:SUG31204.1}, NCTC7307_00510
GN {ECO:0000313|EMBL:SQI19955.1}, NCTC8297_00647
GN {ECO:0000313|EMBL:SUG45477.1};
OS Salmonella enterica subsp. arizonae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=59203 {ECO:0000313|EMBL:SQI19955.1, ECO:0000313|Proteomes:UP000248731};
RN [1] {ECO:0000313|EMBL:HAB4460120.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Salmonella enterica {ECO:0000313|EMBL:HAB4460120.1};
RX PubMed=30286803;
RA Souvorov A., Agarwala R., Lipman D.J.;
RT "SKESA: strategic k-mer extension for scrupulous assemblies.";
RL Genome Biol. 19:153-153(2018).
RN [2] {ECO:0000313|Proteomes:UP000248731, ECO:0000313|Proteomes:UP000254124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC7295 {ECO:0000313|EMBL:SUG12947.1,
RC ECO:0000313|Proteomes:UP000254124}, NCTC7303
RC {ECO:0000313|EMBL:SUG50646.1, ECO:0000313|Proteomes:UP000255443},
RC NCTC7304 {ECO:0000313|EMBL:SUG31204.1,
RC ECO:0000313|Proteomes:UP000254762}, NCTC7307
RC {ECO:0000313|EMBL:SQI19955.1, ECO:0000313|Proteomes:UP000248731}, and
RC NCTC8297 {ECO:0000313|EMBL:SUG45477.1,
RC ECO:0000313|Proteomes:UP000254741};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EDH0572506.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FDA00001204 {ECO:0000313|EMBL:EDH0572506.1};
RG GenomeTrakr network: Whole genome sequencing for foodborne pathogen traceback;
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:ECI4938350.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=475813 {ECO:0000313|EMBL:ECI4938350.1};
RA Ashton P.M., Dallman T., Nair S., De Pinna E., Peters T., Grant K.;
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:KAA8661746.1, ECO:0000313|Proteomes:UP000322837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG 6322T {ECO:0000313|EMBL:KAA8661746.1,
RC ECO:0000313|Proteomes:UP000322837};
RA Pineiro-Iglesias B., Tunovic T., Unosson C., Inganas E., Ohlen M.,
RA Cardew S., Jensie-Markopoulos S., Salva-Serra F., Jaen-Luchoro D.,
RA Karlsson R., Svensson-Stadler L., Chun J., Moore E.;
RT "Draft genome sequence of various Type strains from the CCUG.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:HAB4460120.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Salmonella enterica {ECO:0000313|EMBL:HAB4460120.1};
RG NCBI Pathogen Detection Project;
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:QXW48725.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LHICA_AZ23 {ECO:0000313|EMBL:QXW48725.1};
RA Lamas A., Regal P., Miranda J.M., Vazquez B., Cepeda A., Franco C.M.;
RT "Whole-Genome Sequences of non-enterica strains of Salmonella enterica
RT isolated from poultry houses.";
RL Submitted (JUL-2021) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AAIVIG010000051; ECI4938350.1; -; Genomic_DNA.
DR EMBL; AAMGFJ010000041; EDH0572506.1; -; Genomic_DNA.
DR EMBL; DAAGTC010000003; HAB4460120.1; -; Genomic_DNA.
DR EMBL; VXJW01000021; KAA8661746.1; -; Genomic_DNA.
DR EMBL; CP079713; QXW48725.1; -; Genomic_DNA.
DR EMBL; LS483466; SQI19955.1; -; Genomic_DNA.
DR EMBL; UGWZ01000001; SUG12947.1; -; Genomic_DNA.
DR EMBL; UGXD01000002; SUG31204.1; -; Genomic_DNA.
DR EMBL; UGXG01000002; SUG45477.1; -; Genomic_DNA.
DR EMBL; UGXC01000003; SUG50646.1; -; Genomic_DNA.
DR RefSeq; WP_001086025.1; NZ_VXJW01000021.1.
DR AlphaFoldDB; A0A2X4VZR6; -.
DR Proteomes; UP000248731; Chromosome 1.
DR Proteomes; UP000254124; Unassembled WGS sequence.
DR Proteomes; UP000254741; Unassembled WGS sequence.
DR Proteomes; UP000254762; Unassembled WGS sequence.
DR Proteomes; UP000255443; Unassembled WGS sequence.
DR Proteomes; UP000322837; Unassembled WGS sequence.
DR Proteomes; UP000839688; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003917; F:DNA topoisomerase type I (single strand cut, ATP-independent) activity; IEA:InterPro.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR Gene3D; 3.30.65.10; Bacterial Topoisomerase I, domain 1; 3.
DR InterPro; IPR000380; Topo_IA.
DR InterPro; IPR013498; Topo_IA_Znf.
DR PANTHER; PTHR42785:SF1; DNA TOPOISOMERASE; 1.
DR PANTHER; PTHR42785; DNA TOPOISOMERASE, TYPE IA, CORE; 1.
DR Pfam; PF01396; zf-C4_Topoisom; 4.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000313|EMBL:QXW48725.1};
KW Isomerase {ECO:0000313|EMBL:SQI19955.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000248731}.
FT DOMAIN 13..49
FT /note="DNA topoisomerase type IA zn finger"
FT /evidence="ECO:0000259|Pfam:PF01396"
FT DOMAIN 62..98
FT /note="DNA topoisomerase type IA zn finger"
FT /evidence="ECO:0000259|Pfam:PF01396"
FT DOMAIN 105..142
FT /note="DNA topoisomerase type IA zn finger"
FT /evidence="ECO:0000259|Pfam:PF01396"
FT DOMAIN 145..168
FT /note="DNA topoisomerase type IA zn finger"
FT /evidence="ECO:0000259|Pfam:PF01396"
SQ SEQUENCE 185 AA; 20552 MW; 80FAF45653FD6BC2 CRC64;
MAKLALFSVR KNEPCPQCGA ELVIRSGKHG PFLGCARYPE CEYVRPLKSS ADGHIVKVLE
GKLCPNCGAA LVLRQGRFGM FIGCSEYPAC EHTELIDKPD ETAIVCPQCQ KGHLVQRRSR
YGKTFHSCDR YPECQFAINY KPIAGECPEC HYPLLIEKKT AQGVKRFCAS KQCGKPVPAE
QTSEQ
//
