ID   A0A2Y9BDY5_9FIRM        Unreviewed;       370 AA.
AC   A0A2Y9BDY5;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Uroporphyrinogen decarboxylase {ECO:0000313|EMBL:SSA55054.1};
GN   ORFNames=A8806_103299 {ECO:0000313|EMBL:PWJ30892.1},
GN   SAMN05216536_103299 {ECO:0000313|EMBL:SSA55054.1};
OS   Faecalicatena orotica.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Faecalicatena.
OX   NCBI_TaxID=1544 {ECO:0000313|EMBL:SSA55054.1, ECO:0000313|Proteomes:UP000251306};
RN   [1] {ECO:0000313|EMBL:SSA55054.1, ECO:0000313|Proteomes:UP000251306}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NLAE-zl-C242 {ECO:0000313|EMBL:SSA55054.1,
RC   ECO:0000313|Proteomes:UP000251306};
RA   Cai Z.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:PWJ30892.1, ECO:0000313|Proteomes:UP000245845}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NLAE-zl-C242 {ECO:0000313|EMBL:PWJ30892.1,
RC   ECO:0000313|Proteomes:UP000245845};
RA   Kelly W.;
RT   "The Hungate 1000. A catalogue of reference genomes from the rumen
RT   microbiome.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; QGDL01000003; PWJ30892.1; -; Genomic_DNA.
DR   EMBL; UETE01000003; SSA55054.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2Y9BDY5; -.
DR   OrthoDB; 9780425at2; -.
DR   Proteomes; UP000245845; Unassembled WGS sequence.
DR   Proteomes; UP000251306; Unassembled WGS sequence.
DR   GO; GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:InterPro.
DR   GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:InterPro.
DR   CDD; cd03465; URO-D_like; 1.
DR   Gene3D; 3.20.20.210; -; 1.
DR   InterPro; IPR038071; UROD/MetE-like_sf.
DR   InterPro; IPR000257; Uroporphyrinogen_deCOase.
DR   PANTHER; PTHR47099; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR   PANTHER; PTHR47099:SF1; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR   Pfam; PF01208; URO-D; 1.
DR   SUPFAM; SSF51726; UROD/MetE-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245845}.
FT   DOMAIN          18..356
FT                   /note="Uroporphyrinogen decarboxylase (URO-D)"
FT                   /evidence="ECO:0000259|Pfam:PF01208"
SQ   SEQUENCE   370 AA;  40776 MW;  F9B5AEB905398FE1 CRC64;
     MDYIELRHLM EEQKEEMTPS ERMKAYMAGE EVDVLPYGLL GDEPAMADIF GFTTSQLDND
     PEIAAEIIRR KKAEFGMEGI GVGLGLRTIG AALGSELSIP EHGIDHIASH VLTDYGKLEK
     MEIPDPYHNP VLTPLIERGR RLKEIFPDTS IGTSVAGPVS TAAAIRPVEG LLRDTRKNPE
     LLKRLLDFTV DCSLKWLEVF CNEFGPSPAM ISDPVTCMDI LSKKQFDEFS IPYLNRLVEG
     MEKITGMKPS IHICGKTKPI WGNLGDMDIA AFSVDNCEDI KETREVLGNK VMLIGNVPPV
     DVMKEGTIDE VVAACKECIK KCADSPKGYQ LGTGCQVPIG TPRENVDAFI YAARKYGRGA
     KIGRMPKGIE
//